Studies on drying characteristic, nutritional composition, and antioxidant properties of Stevia rebaudiana (Bertoni) leaves

Moguel-Ordóñez, Yolanda; Cabrera-Amaro, Diana Leticia; Campos, Maira Rubí Segura; Ruíz-Ruíz, Jorge Carlos

doi:10.1515/intag-2015-0039

Cited by 18 publications

(8 citation statements)

References 11 publications

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“…Such observations are also reported earlier. 42 Methanol extracted samples of P. foetida are found superior in antioxidant activity over ethanol, acetone and water. TAA activity is found positively and significantly correlated with TPC and TFC.…”

Section: Discussionmentioning

confidence: 99%

Extraction of Total Phenolics, Flavonoids and Tannins from Paederia foetida L. Leaves and their Relation with Antioxidant Activity

Ojha¹,

Raj²,

Roy³

et al. 2018

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Paederia foetida L., belonging to the family Rubiaceae is a perennial climbing shrub, extensively used in folk medicine for the remedy of stomach disorders, gastritis, indigestion, rheumatic pain, improvement of liver and kidney function 1,2,3 among others. The species possesses antiarthitic, 3 anti-inflammatory, 4 hepatoprotective, 5 antitussive, 6 antidiarrhoeal, 7 activities and also manifests aphrodisiac potentiality by increasing testosterone levels in experimental rats. 8 P. foetida is reported to consist of different phytoconstituents like iridoid glycosides (asperuloside, scandoside and paederoside), volatile oils (linalool, geraniol, α-terpineal), triterpenoids (urosolic acid, oleanolic acid) β-sitosterol, arachidic acid 1,9,10 which are implicated for diverse bioactivities. 11,12,13 It also contains alkaloids (paederine a and b), flavonoids and high proportion of mineral elements. 1,14 However, reports on phenolics in the species are rather meagre. 1 The foetid smell of P. foetida is due to release of methyl-mercaptan from the injured plant tissues following enzymatic cleavage of paederoside.

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Section: Discussionmentioning

confidence: 99%

Extraction of Total Phenolics, Flavonoids and Tannins from Paederia foetida L. Leaves and their Relation with Antioxidant Activity

Ojha¹,

Raj²,

Roy³

et al. 2018

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“…This product has a certification from the US Department of Agriculture. The components present in this variety of stevia have been described by other authors (Table ) . Stevia leaves were sprayed in the mill with 1‐mm mesh and stored in amber glass bottles to protect them from sunlight until used.…”

Section: Methodsmentioning

confidence: 99%

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways

Ramos‐Tovar

Buendia-Montaño

Galindo-Gómez

et al. 2018

Hepatology Research

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Aim The aims of the present study were to investigate the capacity of stevia leaves to prevent experimental cirrhosis induced by chronic administration of carbon tetrachloride (CCl4) in rats and to explore the action mechanism involved. Methods Liver cirrhosis was established by CCl4 treatment (400 mg/kg i.p. three times a week for 12 weeks); stevia powder was administered (100 mg/kg by gavage daily) during the CCl4 treatment. Serum markers of liver damage and hydroxyproline were evaluated and histopathological analyses were carried out. The profibrotic pathways were analyzed by western blot and immunohistochemistry. Results We found for the first time that stevia cotreatment prevented the elevation of serum markers of necrosis and cholestasis and the occurrence of liver fibrosis. It is worth noting that stevia downregulated several profibrogenic pathways, including the reduction of hepatic myofibroblasts and decreased matrix metalloproteinase (MMP)2 and MMP13 expression, thereby blocking the liberation of transforming growth factor‐β from the extracellular matrix. Notably, stevia reduced the phosphorylation of pSmad3L, the most profibrogenic and mitogenic Smad, by inhibiting the activation of c‐Jun N‐terminal kinase and extracellular signal‐regulated kinase. Interestingly, Smad7, an important antifibrotic molecule, was upregulated by stevia treatment in cirrhotic rats. These multitarget mechanisms led to the prevention of experimental cirrhosis. Conclusions Because stevia possesses a reasonable safety profile, our results indicate that it could be useful in the clinical setting to treat chronic liver diseases.

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“…Using exactly the same drying methods presented here, Moguel-Ordóñez et al (2015) demonstrate that sun dried leaves have more luminescence, chlorophyll-associated green colour, and total pigments but lower antioxidant capacity compared to convection drying, which yields the greatest antioxidant capacity but lower luminosity and green colour.…”

Section: Resultsmentioning

confidence: 63%

Effect of different drying methods on the composition of steviol glycosides in Stevia rebaudiana Bertoni leaves

Aranda-González¹,

Betancur‐Ancona²,

Chel‐Guerrero³

et al. 2017

International Agrophysics

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A b s t r a c t. Drying techniques can modify the composition of certain plant compounds. Therefore, the aim of the study was to assess the effect of different drying methods on steviol glycosides in Stevia rebaudiana Bertoni leaves. Four different drying methods were applied to Stevia rebaudiana Bertoni leaves, which were then subjected to aqueous extraction. Radiation or convection drying was performed in stoves at 60ºC, whereas shade or sun drying methods were applied at 29.7ºC and 70% of relative humidity. Stevioside, rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, dulcoside A, and steviolbioside were quantified by a validated HPLC method. Among steviol glycosides, the content (g 100 g -1 dry basis) of stevioside, rebaudioside A, rebaudioside B, and rebaudioside C varied according to the drying method. The total glycoside content was higher in sun-dried samples, with no significant differences compared to shade or convection drying, whereas radiation drying adversely affected the content of rebaudioside A and rebaudioside C (p <0.01) and was therefore a method lowering total glycoside content. The effect of the different drying methods was also reflected in the proportion of the sweetener profile. Convection drying could be suitable for modern food processing industries while shadow or sun drying may be a low-cost alternative for farmers.

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Studies on drying characteristic, nutritional composition, and antioxidant properties of Stevia rebaudiana (Bertoni) leaves

Cited by 18 publications

References 11 publications

Extraction of Total Phenolics, Flavonoids and Tannins from Paederia foetida L. Leaves and their Relation with Antioxidant Activity

Extraction of Total Phenolics, Flavonoids and Tannins from Paederia foetida L. Leaves and their Relation with Antioxidant Activity

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways

Effect of different drying methods on the composition of steviol glycosides in Stevia rebaudiana Bertoni leaves

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