Based on the technological requirements related to waxy crude oil pipeline transportation, both unavoidable and avoidable destroyed exergy are defined. Considering the changing characteristics of flow pattern and flow regime over the course of the oil transportation process, a method of dividing station oil pipelines into transportation intervals is suggested according to characteristic temperatures, such as the wax precipitation point and abnormal point. The critical transition temperature and the specific heat capacity of waxy crude oil are calculated, and an unavoidable destroyed exergy formula is derived. Then, taking the Daqing oil pipeline as an example, unavoidable destroyed exergy in various transportation intervals are calculated during the actual processes. Furthermore, the influential rules under various design and operation parameters are further analyzed. The maximum and minimum unavoidable destroyed exergy are 381.128 kJ/s and 30.259 kJ/s. When the design parameters are simulated, and the maximum unavoidable destroyed exergy is 625 kJ/s at the diameter about 250 mm. With the increase of insulation layer thickness, the unavoidable destroyed exergy decreases continuously, and the minimum unavoidable destroyed exergy is 22 kJ/s at 30 mm. And the burial depth has little effect on the unavoidable destroyed exergy. When the operation parameters are simulated, the destroyed exergy increases, but it is less affected by the outlet pressure. The increase amplitude of unavoidable destroyed exergy will not exceed 2% after the throughput rises to 80 m 3 /h. When the outlet temperature increases until 65 • C, the loss increase range will not exceed 4%. Thus, this study provides a theoretical basis for the safe and economical transportation of waxy crude oil. of insulation materials required for such pipelines, so as to achieve the smallest energy operation. Nguyen et al. [5] show that the oil platform is an energy-intensive system. Referring to the nature of oil, export specifications and oil field life, the energy used by each facility ranges from several megawatts to several hundred megawatts, and the overall system is energy-saving in terms from equipment size and process integration.In recent years, exergy has been regarded as an energy consumption evaluation index in thermodynamics. Exergy denotes that part of energy quantity that can be transformed into useful work to the utmost degree when substance or material flow changes reversibly from any state to a given environment equilibrium state. The concept exergy, which organically combines "quality" and "quantity" of energy and reflects the real value of energy, has made all kinds of energy comparable and solved the puzzling problem that none of the parameters can be singly used to assess the value of energy in thermodynamics and energy science. It also changed traditional ideas about energy character, energy loss and energy transformation efficiency, etc [6][7][8][9].The exergy analysis method addresses the deficiency of the first law of thermodynamics, whic...