Studies on Hydatigera taeniaeformis. III. The water content of larval and adult worms

Hopkins, C. A.; Hutchison, W. M.

doi:10.1016/0014-4894(60)90033-3

Cited by 6 publications

(2 citation statements)

References 8 publications

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“…Major net growth increments apparently finish about day 18, though as only the second experiment was continued beyond day 17 it is not possible to decide whether the worms really reached a maximum size on day 20 and then oscillated, or whether the mean weights recorded from day 18 to day 27 inclusive were all chance variations about a mean adult weight. The dry weight as a percentage of the fresh weight (col. 5) rises with age, as occurs generally in tapeworms and other animals (Hopkins & Hutchison, 1960).…”

Section: (B) the Growth Of Single-worm Infections (I) Weightmentioning

confidence: 79%

The migration of Hymenolepis diminuta in the rat's intestine during normal development and following surgical transplantation

Bråten

1969

Parasitology

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The normal position of attachment of the scolex of H. diminuta from day 6 to day 27 in single worm infections in male Wistar rats was determined. A migration forward from a position of attachment 30–40% down the length of the small intestine to the 10–20% region during day 7 to day 14 was confirmed. A concomitant and slightly faster movement backwards of the posterior of the worm led to the mid-point of the strobila changing from 35 to 50% down the intestine. By day 18 the worms were mature and occupied the whole small intestine except the anterior 10% and the posterior 5–10%. The worms weighed approximately 350 mg dry weight (= 1550 mg fresh weight) at maturity, no significant weight increase occurred thereafter.6½ and 7½ day-old worms were transplanted from donor rats into the duodenum or posterior ileum. Nearly 100% recovery of the single worm transplants in recipient rats was obtained. Both anterior and posterior implanted worms returned to the region of the intestine from which they had been removed. Migration was measured over periods of 13–72 h and was found to be complete within 24 h. Worms transplanted into the duodenum continued to grow at nearly the normal rate but worm transplants into the posterior ileum lost nearly a day's growth. The significance of this point is discussed.Opium was found to prevent migration of the tapeworm, but ligation of the bile duct did not prevent the tapeworm migrating forward from a point of insertion near the ileo-caecal junction.The evidence confirms the concept that a tapeworm is a dynamic organism capable of recognizing a specific region of the intestine, of detecting when it is not in this region, of being able to interpret one or more stimuli to indicate direction and of having a motor system sufficiently coordinated to overcome peristalsis.We gratefully acknowledge financial support by the Medical Research Council (London) and technical assistance from Miss Helen Stallard, B.Sc., Miss Pat Grant and Miss Gillian Moore. One of us (Trond Braten) wishes also to thank the University of Glasgow for the award of a Visiting Fellowship.

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Section: (B) the Growth Of Single-worm Infections (I) Weightmentioning

confidence: 79%

The migration of Hymenolepis diminuta in the rat's intestine during normal development and following surgical transplantation

Bråten

1969

Parasitology

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“…4). Dry weight increases to a plateau about 31 % of fresh weight which is much higher than in cyclophyllidean cestodes (Hopkins & Hutchison, 1960) where the glycogen content is also much lower e.g. 32% D.W. (range 19-43%) in adult Raillietina cesticillus (Reid, 1942), 40-44% larval Hydatigera taeniaeformis (Hopkins, 1960), a maximum of about 40% in adult Hymenolepis diminuta (Roberts, 1961).…”

Section: Discussionmentioning

confidence: 86%

Studies onSchistocephalus solidus

Mccaig

Hopkins

1965

Parasitology

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Schistocephalus plerocercoids in the weight range 2–200mg F.W. recovered from the perivisceral cavity of Gasterosteus aculeatus were cultured in various media. In a medium composed of 25% horse serum, 0·5% yeast extract, 0·65% glucose and Hanks's saline at pH 7·1, 21°C, 95% air +5% CO2, dry weight increases of up to 500% were recorded in 8 days. The specific growth rate of large plerocercoids was only one-tenth of the rate observed in small plerocercoids. A plerocercoid of double the weight of another had approximately half the specific growth rate.Worms after 8 days cultivation were found to have only slightly higher than normal glycogen and water content, and to be able to mature when heated to 40°C. However, the rate of growth slowed to zero by the 24th day in culture at 21°C. Electron microscopic examination showed a ‘deposit’ formed over the microvilli, thin at 8 days but dense after 21 days.The in vivo glycogen and water content of plerocercoids from 3–300 mg F.W. was determined. Glycogen rose from 24% in plerocercoids of 10mg F. W. to 50–55% in plerocercoids over 80mg F. W. The water content was found to mimic precisely this change, falling from 82% to a plateau of 67–69%.We wish to thank Professor Gareth Owen for permission to use the photograph shown in the Plate and for his help while using the electron microscope. It is also a pleasure to thank Miss Patricia Grant for her technical assistance.

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Experimentelle Invasionen bzw. Erzeugung von Krankheiten durch Metazoen bei Laboratoriumstieren

Erhardt

Lämmler²,

Hinz

et al. 1964

Infektionen I

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Studies on Hydatigera taeniaeformis. III. The water content of larval and adult worms

Cited by 6 publications

References 8 publications

The migration of Hymenolepis diminuta in the rat's intestine during normal development and following surgical transplantation

The migration of Hymenolepis diminuta in the rat's intestine during normal development and following surgical transplantation

Studies onSchistocephalus solidus

Experimentelle Invasionen bzw. Erzeugung von Krankheiten durch Metazoen bei Laboratoriumstieren

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