Groups of eight laying Single-Comb White Leghorn pullets were each administered the following fission products : strontium-89, yttrium-91, niobium-95, molybdenum-99, ruthenium-103, iodine-131, tellerium-132, cesium-134, barium-140, lanthanum-140, praseodymium-142, cerium-144, neodymium-147 or promethium-147 at levels selected to permit counting of tissues upon sacrifice 96 hr after dosing. Half the hens were administered the fission products intramuscularly (IM) while the other half received them orally. Whole blood, plasma, gastrocnemius muscle, superficial pectoralis muscle, liver, gall-bladder, kidney, lung, spleen, heart, brain, gizzard, tibia shaft, posterior portion of sternal crest, ovary, reproductive tract and eggs were analyzed for fission product content.The differences in fission product concentration in tissues and egg components between I M and oral routes were quite small for 134Cs, sgSr and 1311. These same differences for the fission products increased in magnitude in the following order: 99Mo, 140Ba, 132Te, 142Pr and Io3Ru.