1979
DOI: 10.1159/000131371
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Studies on isolated cloned populations from irradiated human embryonic cell cultures

Abstract: The recovery of substrains with stable chromosome aberrations from irradiated fibroblast cultures are reported. Four human fetal cell strains were exposed to 600 rad of gamma rays at 200 rad/min. The efficiency of recovering viable cloned subpopulatiohs was approximately 87 %, and the frequency of clones with abnormal chromosomes was 40/100 colonies. G-band chromosome analyses for 34 abnormal substrains are described. Karyotypes of some of the clones with complex rearrangements are also presented. Analyses of … Show more

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