Studies on Metal Complexes of Pyrazole Bearing Ligand with Their Antimicrobial Screening

Abstract

In present research article, we reported the synthesise of novel hetertocyclic ligand namely,5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl) methyl)-8-hydroxy quinoline (BIPPHQ) from 5-chloro methyl-8-hydroxy quinoline and 1-((5-phenyl-1H-pyrazol-3-yl) methyl)-1H-benzimidazole (BIPP). The BIPP was synthsised by the reaction between hydrazine hydrate with 1-(1H-benzimidazol-1-yl)-4-phenylbut-3-en-2-one (BIPB), which was synthesisd from 1-(1H-benzimidazol-1-yl)propan-2-one (BIP) and benzaldehyde. The transition metal complxes of 5-((3-((1H-benzimidazol-1-yl)methyl)-5-phenyl-1H-pyrazol-1-yl)methyl)-8-hydroxy quinoline (BIPPHQ) were sythsised and analysed with the help of elemen conten analysis, spectroscopic data analysis, ratio of metal and ligand and also magneic parameters. The BIPPHQ and etal coplexes also screened for antimicrobial study.