Studies on nutritional intervention of rice starch- oleic acid complex (resistant starch type V) in rats fed by high-fat diet

Zheng, Bo; Wang, Tongtong; Wang, Hongwei; Chen, Ling; Zhou, Zhongkai

doi:10.1016/j.carbpol.2020.116637

Cited by 104 publications

(50 citation statements)

References 31 publications

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“…The preceding results with sucrose FA esters infer that the V-helix is being fermented otherwise resulting FFA would be excreted. Fermentation of the carbohydrate component is supported using rats fed a V-helix: oleic acid complex ( Zheng et al., 2020 ). In addition to a reduced live performance, an enhanced presence of Bifidobacteria occurred in the large intestine which is known to produce butyric acid from amylose-based RS.…”

Section: Gastrointestinal System and V-helix-fa Complexesmentioning

confidence: 99%

“…Early studies on the feeding of synthetic V-helix-FA complexes to rats and dogs impaired live performance and apparent digestibility ( Holm et al., 1983 ; Murray et al., 1998 ); however, any advantage to health was not mentioned. More recently, feed supplemented with V-helix-FA complexes for rats was observed to enhance Bifidobacteria in fecal excreta which could produce butyric acid and favorable terms for large intestinal mucosa ( Zheng et al., 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Dietary free fatty acids complex with amylose creating another form of resistant starch: Gastrointestinal formation with fowl and swine

Moran

2021

Animal Nutrition

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Fat added to poultry and swine feeds often contains abundant free fatty acids (FFA) that can impair digestible energy (DE). Placement of the fatty acid (FA) hydrocarbon chain in the helix core reformed from amylose creates a complex of both nutrients. Resulting modifications create a new structure termed the V-helix that becomes resistant to α-amylase. Granules in grain naturally contain minimal amounts of these complexes with more being generated during food manufacturing when moisture and heat release amylose in the presence of FFA. A paucity of FFA usually exists in complete feeds without sources of poor-quality fat. Animal fats and by-product meals from rendering are prominent in their saturated FFA content which favorably complex within the helix. V-helix-FA complexes may arise during their concurrent encounter of FFA together with amylose during feed manufacture, particularly pelleting. FFA in the gastrointestinal tract (GIT) are speculated to further form complexes when present together with amylose. Although amylose may be dissolved in the gastric and small intestinal milieu, FFA separately coalesce into hydrophobic fat droplets along with other dietary lipids. Formation of complexes is likely restricted until FFA are released into the aqueous phase during fat digestion. Although α-amylase may be prominent, V-helix-FA complexes being resistant to enzymic attack pass into the large intestine. Subsequent microbial catabolism of V-helices may generate volatile fatty acids that are absorbed by the mucosa; however, an inability to use FFA once released leads to their excretion and basis for decreased DE. Immature microbial populations with young animals usually lack the capacity to fully catabolize the V-helix, further extending the loss in DE.

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Section: Gastrointestinal System and V-helix-fa Complexesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dietary free fatty acids complex with amylose creating another form of resistant starch: Gastrointestinal formation with fowl and swine

Moran

2021

Animal Nutrition

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“…As putatively beneficial gut microbiota, Akkermansia reinforces the gut barrier function and eventually reduces plasma lipopolysaccharide (37,38). Previous studies also show that high relative abundances of Romboutsia are associated with decreased risk for infection in kidney transplant recipients (39), the Turicibacter might play a role in inflammatory bowel diseases and was proportional in concentration to that of butyric acid (40,41). Weissella and pediococcus are recognized probiotic genera, which play a role in improving the health of the host (42,43).…”

Section: Differences In the Gut Microbiota Between Con And Met Offspring During Suckling Periodmentioning

confidence: 99%

Methyl-Donor Micronutrient for Gestating Sows: Effects on Gut Microbiota and Metabolome in Offspring Piglets

Zou

et al. 2021

Front. Nutr.

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This study aimed to investigate the effects of maternal methyl-donor micronutrient supplementation during gestation on gut microbiota and the fecal metabolic profile in offspring piglets. Forty-three Duroc × Erhualian gilts were assigned to two dietary groups during gestation: control diet (CON) and CON diet supplemented with MET (folic acid, methionine, choline, vitamin B6, and vitamin B12). The body weights of offspring piglets were recorded at birth and weaning. Besides this, fresh fecal samples of offspring piglets were collected at 7, 14, and 21 days. The gut microbiota composition, metabolic profile, and short-chain fatty acid (SCFA) profiles in the fecal samples were determined using 16S rDNA sequencing, liquid chromatography-mass spectrometry metabolomics, and gas chromatography methods, respectively. The results showed that maternal methyl-donor micronutrient supplementation increased the microbiota diversity and uniformity in feces of offspring piglets as indicated by increased Shannon and Simpson indices at 7 days, and greater Simpson, ACE, Chao1 and observed species indices at 21 days. Specifically, at the phylum level, the relative abundance of Firmicutes and the Firmicutes to Bacteroidetes ratio were elevated by maternal treatment. At the genus level, the relative abundance of SCFA-producing Dialister, Megasphaera, and Turicibacter, and lactate-producing Sharpea as well as Akkermansia, Weissella, and Pediococcus were increased in the MET group. The metabolic analyses show that maternal methyl-donor micronutrient addition increased the concentrations of individual and total SCFAs of 21-day piglets and increased metabolism mainly involving amino acids, pyrimidine, and purine biosynthesis. Collectively, maternal methyl-donor micronutrient addition altered gut microbiota and the fecal metabolic profile, resulting in an improved weaning weight of offspring piglets.

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“…As modificações relacionadas ao estilo de vida e a dieta têm sido intimamente associadas ao crescente aumento de doenças crônicas não transmissíveis em todo o mundo, incluindo diabetes tipo 2, hipertensão, dislipidemia, resistência à insulina, doenças cardiovasculares e obesidade. Com isso, a função dos alimentos e nutrientes na prevenção e tratamento, bem como nas complicações associadas a essas doenças tornou-se foco de preocupação de pesquisas nas últimas décadas (Si et al, 2017;Sun et al, 2018;Zheng et al, 2020;Medina Martinez et al, 2021).…”

Section: Introductionunclassified

Alterações induzidas pela dieta com diferentes concentrações de amido resistente no metabolismo de carboidratos e de lipídeos, em ratos Wistar

Alves

Pigoso

Chang

et al. 2021

RSD

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Este trabalho teve como objetivo avaliar o efeito da substituição do amido pré-gelatinizado por amido resistente no metabolismo de lipídeos e de carboidratos em ratos machos Wistar. 20 ratos machos foram divididos em dois grupos, um grupo recebeu uma dieta com 9,5% (DAP) e o outro grupo com 18,1% (DAR) de amido resistente durante 22 dias. Foram analisados peso, consumo de ração e água, e quantificadas as concentrações de colesterol e de triglicerídeos no soro e no músculo, e de glicogênio hepático e muscular. Os dados foram analisados por teste de Tukey (p>0,05) e gráficos box-plot. Não houve diferenças significativas na ingestão de ração e água, mas os animais do grupo DAP apresentaram aumento de peso (51,12g para 55,27g) enquanto os do grupo DAR diminuíram (49,01g para 44,15g). O grupo DAR apresentou diminuição de triglicérideos, colesterol total no soro (de 125,761 mg/dL para 104,874 mg/dL) e do glicogênio muscular, mas aumento de triglicerídeos no músculo gastrocnêmio em comparação com o grupo DAP (de 0,160 mg/dL para 0,259 mg/dL). Estes resultados apontam para a diminuição na velocidade de absorção da glicose no grupo de animais com dieta com maior quantidade de amido resistente, que pode ter induzido diminuição nos processos de síntese de triglicérideos e de colesterol levando ao aumento do catabolismo destes substratos pelo organismo, e adaptação plástica dos músculos para utilização de ácidos graxos no seu metabolismo oxidativo.

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Studies on nutritional intervention of rice starch- oleic acid complex (resistant starch type V) in rats fed by high-fat diet

Cited by 104 publications

References 31 publications

Dietary free fatty acids complex with amylose creating another form of resistant starch: Gastrointestinal formation with fowl and swine

Dietary free fatty acids complex with amylose creating another form of resistant starch: Gastrointestinal formation with fowl and swine

Methyl-Donor Micronutrient for Gestating Sows: Effects on Gut Microbiota and Metabolome in Offspring Piglets

Alterações induzidas pela dieta com diferentes concentrações de amido resistente no metabolismo de carboidratos e de lipídeos, em ratos Wistar

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