Studies on Sudanese Bee Honey: Laboratory and Clinical Evaluation

Farouk, Asim; Hassan, T.; Kashif, H.; Khalid, Sami A.; Mutawali, I.; Wadi, Mahasin

doi:10.3109/13880208809053912

Cited by 35 publications

(36 citation statements)

References 6 publications

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“…Moreover, honey dressings have revealed economic benefits by lower direct costs compared to conventional treatments [70,90], by decreasing the use of antibiotics [91], the healing and hospitalization time [70,85,91].…”

Section: Evidence From Clinical Trialsmentioning

confidence: 99%

“…As described in clinical trials, the procedure for [46,48,70,86,91]. This stage was especially necessary in the case of burns and infected, necrotic wounds;…”

Section: Personal Experience With L-mesitran Dressingsmentioning

confidence: 99%

“…Thus, the non-adherent dressings enable easy removal, without any discomfort or inconvenience [11]. Honey dressings were reported to be easy to apply and remove [70,86,87], without adhesions [88] or bleeding [45], any residual amount of honey being easily removed by simply rinsing [29]. Studies highlighted that honey did not cause any local pain on dressing [88,89] or caused only a momentary stinging [89], was not irritating [47,89], did not cause any allergic reaction [59,70,85] and had no harmful effects on tissues [47,70,85,89].…”

Section: Evidence From Clinical Trialsmentioning

confidence: 99%

“…Moreover, honey has a wound debriding action, evidenced in clinical trials [43][44][45][46][47][48][69][70][71][72][73]. Honey activates plasminogen and increases plasmin activity, which lyses fibrin attaching slough, by suppression of the macrophage plasminogen activation inhibitor.…”

Section: Debriding Activity Of Honeymentioning

confidence: 99%

“…As a useful alternative to cotton dressings, special types of dressings impregnated with medical grade honey were used in some clinical situations, such as tulle and hydroactive dressings from L-Mesitran range of products. The wound cavities were filled with medical grade honey or with honey-impregnated dressings [91] and then covered with gauze [70,89]; (4) Changing of honey dressings was practiced mostly daily [69-71, 86, 89, 90], but also once every 2-3 d [43,45,47,59,87], according to the appearance and evolution of wounds. Thus, the clean wounds with reduced exudate and good evolution require less frequent change.…”

Section: Personal Experience With L-mesitran Dressingsmentioning

confidence: 99%

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Honey, Food and Medicine: Scientific Rationale and Practical Efficiency in External Administration of Medicinal Honey for Wound Healing

Zbuchea¹

2017

JAST-B

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Except for its benefits as food and medicine, honey has been used since ancient times as an external remedy in wound care, and has been the subject of numerous studies and research, that reveal its complex favorable action for wound healing. Based on scientific research and clinical studies published in literature, this work presents these various properties and therapeutic activities of honey dressings. Next, actions and clinical effects of L-Mesitran range of dressings, based on medicinal honey and authorized European Union (EU) and Food and Drug Administration (FDA), have been highlighted in a case series of patients in the Department of Plastic Surgery, Emergency District Hospital of Ploiesti, Romania, by monitoring the clinical local evolution of burns and other wounds. L-Mesitran range of products is based on the combination of medicinal honey and other ingredients, such as hypoallergenic medicinal lanolin, vitamins C and E. These sterilized preparations were applied for various skin lesions after wound cleansing, and exerted a favorable action on healing of burns and other wounds, sometimes in combination with surgical treatment, being applied in these cases before or after surgery. Further clinical studies are needed to establish the best indications, methods and forms of administration for each type of wounds, as well as the selection over other types of dressings.

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Section: Evidence From Clinical Trialsmentioning

confidence: 99%

“…As described in clinical trials, the procedure for [46,48,70,86,91]. This stage was especially necessary in the case of burns and infected, necrotic wounds;…”

Section: Personal Experience With L-mesitran Dressingsmentioning

confidence: 99%

Section: Evidence From Clinical Trialsmentioning

confidence: 99%

Section: Debriding Activity Of Honeymentioning

confidence: 99%

Section: Personal Experience With L-mesitran Dressingsmentioning

confidence: 99%

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Honey, Food and Medicine: Scientific Rationale and Practical Efficiency in External Administration of Medicinal Honey for Wound Healing

Zbuchea¹

2017

JAST-B

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Honey: Biological Characteristics and Potential Role in Disease Management

Shahid

2008

New Strategies Combating Bacterial Infection

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Honey is one of the oldest known medicines that has continued to be used in folk medicine and has been used as an adjuvant for accelerating wound healing. It is reported to prevent infection and promote healing since it has ingredients very similar to antibiotics. The major antibacterial properties of honey can be attributed to its low pH, high sugar content, enzymatic production of hydrogen peroxide, a thermolabile substance called inhibine and its hygroscopic properties. Several chemicals with antibacterial activity have also been identified [i.e. pinocembrin, terpenes, benzyl alcohol, 3,5-dimethoxy-4-hydroxybenzoic acid (syringic acid), methyl 3,5-dimethoxy-4-hydroxybenzoate (methyl syringate), 3,4,5-trimethoxybenzoic acid, 2-hydroxy-3-phenylpropionic acid, 2-hydroxybenzoic acid and 1,4-dihydroxybenzene]. However, the quantities of these substances are far too low to account for any significant amount of activity. Honey also serves as an important medicine because of its mild laxative, bactericidal, sedative and antiseptic characteristics. Recently, the emergence of multidrug-resistant (MDR) organisms has created a lot of chaos in the medical field. Hence, there is a need to find an alternative to counter these MDR organisms. This chapter will discuss the factors responsible for antimicrobial properties and potential use of honey as an antimicrobial agent. This chapter will also cover the effect of honey on MDR bacteria, discussing the few reports from available literature.

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Honey as an Antimicrobial Agent

Molan

1997

Bee Products

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Studies on Sudanese Bee Honey: Laboratory and Clinical Evaluation

Cited by 35 publications

References 6 publications

Honey, Food and Medicine: Scientific Rationale and Practical Efficiency in External Administration of Medicinal Honey for Wound Healing

Honey, Food and Medicine: Scientific Rationale and Practical Efficiency in External Administration of Medicinal Honey for Wound Healing

Honey: Biological Characteristics and Potential Role in Disease Management

Honey as an Antimicrobial Agent

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