Studies on Suzuki‐Miyaura Reactions Catalyzed by Ferrocenyl or Cobaltocenyl Phosphines Ligated Palladium Complexes

Abstract

DFT studies on several dppf- and dppc-derived bidentate phosphines ligated palladium complexes catalyzed Suzuki-Miyaura coupling reactions were pursued. The catalytic reactions employing ligands, having two phosphine biting sites on different cyclpentadienyl or cyclobutadiene rings, such as 1,1'-dmpf or 1,1'-dmpc, have been verified to be energetically more favorable than those on the same ring provided that tetra-coordinated palladium conformations for all transition states and intermediates are maintained. Apart from the purpose of storage, the application of phosphinous acid (R2P(OH)) in Suzuki-Miyaura reaction is inferior to tertiary phosphine (R3P)

A Highly Active Catalyst 2,4,6‐Tris (di‐4‐chlorobenzamido)‐1,3,5‐triazine Palladium (II) Chloride for the Green Synthesis of Substituted Dihydrobenzo[b]thiophene in Ionic Liquid

“…[3,4] However, the metal, particularly palladium complexes catalyzed cross-coupling reactions are arguably the most widespread synthetic methods in organic synthesis for the forming of CÀ X bonds (X: C, N, O, S, etc). [5] As a consequence, the carbon-sulfur bond induces coupling reactions between thiols and aryl halides that are catalyzed by Pd were studied. [6,7] Moreover, several palladium-catalyzed synthetic routes have been reported for the synthesis of benzothiophene derivatives .…”