Studies on Template Polymerization

Srivastava, A. K.; Nigam, Sonu; Shukla, Abhishek; Saini, S.; Kumar, P.; Tewari, Neeta

doi:10.1080/07366578708081914

Cited by 16 publications

(4 citation statements)

References 27 publications

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“…The very general concept of this process, inspired by the natural routes to nucleic acids and proteins as in the basics of the Central Dogma of Synthetic Biology is to use a template directed synthesis of macromolecules from their monomers [141][142][143][144] involving the molecular recognition, ligation, and product dissociation steps [145]. By using template polymerization of synthetic monomers onto biological templates, bioartificial polymeric blends with a higher degree of miscibility between the two components than by simple mixing of pre-formed polymers are obtained [146,147].…”

Section: Not-conventional Approaches Towards Nanoscale Tailoring Of Bmentioning

confidence: 99%

Biomimetic Tailoring of the Surface Properties of Polymers at the Nanoscale: Medical Applications

Chiono

Descrovi

Sartori

et al. 2010

Scanning Probe Microscopy in Nanoscience and Nanotechnology 2

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New-generation biomaterials are information-rich and incorporate biologically active components derived from Nature. The chapter reviews current approaches for the realization of biomimetic coatings for tissue engineering applications, via functionalization with bioactive molecules such as native long chains of extracellular matrix (ECM) proteins as well as short peptide sequences derived from intact ECM proteins. Biomimetic materials provide cues for cell-matrix interactions, favouring cell adhesion, proliferation, spreading, and differentiation. The recently developed scanning probe techniques for optical and spectroscopic characterization of surfaces are also described, providing advanced topographical imaging and sensitive force measurements. The spectroscopic imaging of surfaces at the nanoscale provides insight into the function and structure of biomimetic molecules and represents a tool for tailoring the surface design.

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Section: Not-conventional Approaches Towards Nanoscale Tailoring Of Bmentioning

confidence: 99%

Biomimetic Tailoring of the Surface Properties of Polymers at the Nanoscale: Medical Applications

Chiono

Descrovi

Sartori

et al. 2010

Scanning Probe Microscopy in Nanoscience and Nanotechnology 2

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“…A mixture of a synthetic polymer and a biopolymer can be obtained, in which the miscibility between the two components depends on the various parameters linked to the nature of the polymers themselves, the functional groups present, the molecular weight, composition, temperature etc. To improve the degree of miscibility in these systems, a different method for the preparation of a bioartificial polymeric material is to perform polymerization onto a template (template polymerization) [3][4][5][6].…”

Section: Bioartificial Polymeric Materialsmentioning

confidence: 99%

The relevance of the transfer of molecular information between natural and synthetic materials in the realisation of biomedical devices with enhanced properties

Ciardelli

Silvestri²,

Cristallini³

et al. 2005

Journal of Biomaterials Science, Polymer Edition

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Past and recent attempts to introduce in synthetic polymers molecular information from natural substances through simple blending, template polymerization and molecular imprinting are reviewed. The most promising approaches that can open the way to the realisation of new materials with improved biocompatibility, antibody- or enzyme-like performances are analysed more deeply. The realisation of bioartificial blends from natural and synthetic polymers, molecularly imprinted nanospheres or membranes that can act as recognition element in (bio)sensing devices, as synthetic enzymes or as key constituents of body fluids purification tools is presented in order to make the reader aware of the fascinating possibilities that these techniques make available to the biomedical science and engineering in the close future. The last part of the paper describes recent attempts to insert recognition elements for large molecules as proteins, DNA segments, viruses or whole cells in synthetic polymer systems, in order to develop new systems in the treatments of diseases and for tissue-engineering applications.

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“…[13] Template polymerisations (TP) may be used to prepare polymer blends which can be different from those obtained by simple mixing. Several template polymerisations involving synthetic systems have been extensively reviewed by Tan and Challa, [14] Kabanov, [15] Srivastava et al [16] As "template polymerisation" is usually defined a reaction in which the growing chains propagate, during most of their lifetime, along macromolecules added to the system as pre-formed polymer. [17 -22] This particular propagation mode is allowed by specific co-operative interactions (i. e. ionic interactions or hydrogen bonds) between the growing chain units and the polymer (usually defined as template).…”

Section: Introductionmentioning

confidence: 99%

Polymerisation onto Biological Templates, a New Way to Obtain Bioartificial Polymeric Materials

Cristallini

Barbani

Giusti³

et al. 2001

Macromol. Chem. Phys.

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Studies on Template Polymerization

Cited by 16 publications

References 27 publications

Biomimetic Tailoring of the Surface Properties of Polymers at the Nanoscale: Medical Applications

Biomimetic Tailoring of the Surface Properties of Polymers at the Nanoscale: Medical Applications

The relevance of the transfer of molecular information between natural and synthetic materials in the realisation of biomedical devices with enhanced properties

Polymerisation onto Biological Templates, a New Way to Obtain Bioartificial Polymeric Materials

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