1997
DOI: 10.1016/s0304-3835(97)00331-5
|View full text |Cite
|
Sign up to set email alerts
|

Studies on the cytostatic and cytotoxic effects and mode of action of 8-nitro-7-hydroxycoumarin

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

1
55
0
1

Year Published

2001
2001
2016
2016

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 118 publications
(57 citation statements)
references
References 11 publications
1
55
0
1
Order By: Relevance
“…Coumarins are a class of lactones which are found widely in nature and possess antiinflammatory [1,2], antiviral [3], antiHIV [4], antifungal [5] and cytotoxic activities [6,7], which have been reviewed [8]. In the development of newer antimicrobials, coumarins have been identified as target specific plant anti-bacterial agents with growth inhibitory potential particularly against Gram-positive species [9].…”
Section: Introductionmentioning
confidence: 99%
“…Coumarins are a class of lactones which are found widely in nature and possess antiinflammatory [1,2], antiviral [3], antiHIV [4], antifungal [5] and cytotoxic activities [6,7], which have been reviewed [8]. In the development of newer antimicrobials, coumarins have been identified as target specific plant anti-bacterial agents with growth inhibitory potential particularly against Gram-positive species [9].…”
Section: Introductionmentioning
confidence: 99%
“…Coumarin was identified in all extracts. Studies in various tumor cell lines have pointed to coumarin and its derivatives as potential substances for cancer treatment [14][15][16][17][18]. Other compounds with antitumor activity were identified in the extracts analyzed: curcumene, psoralen, kaurenoic acid, scopoletin, o-coumaric acid, pinene [19][20][21][22][23].…”
Section: Resultsmentioning
confidence: 99%
“…After 24, 48 and 72 h of treatment, cells were washed, collected by trypsinization, stained with 0.4% trypan blue and counted in triplicate. For each sample, 7x10 4 cells were then lysed in 1% Triton X-100 in 0.1 M Na phosphate buffer (pH 6.8) for 20 min; lysates were incubate with an equal volume of DOPA, 3 mg/ml in 0.1 M Na phosphate buffer for 3 h at 37˚C. Tyrosinase activity was determined by measuring sample absorbance at 490 nm.…”
Section: Methodsmentioning
confidence: 99%
“…B16 and A375 cells were seeded at a density of 1x10 4 cells/well in 6-well plates and treated as described above. After 24-, 48-and 72-h treatment, cells were washed, collected by trypsinization and suspended in RIPA lysis buffer [1% Nonidet P-40, 1% sodium deoxycholate, 0.1% SDS, 0.15 NaCl, 0.01 M sodium phosphate (pH 7.2), 2 mM EDTA, 50 mM sodium fluoride, 0.2 mM sodium vanadate and 100 U/ml aprotinin].…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation