1920
DOI: 10.1002/aja.1000260303
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Studies on the glandular cells of the frog's pancreas

Abstract: Estudios sobre las celulas glandulares del p h x e a s de la rana.El presente trabajo es un estudio criico y priictico de la estructura histolhgica de las celulas glandulares examinadas con ayuda de varios reactivos en diferentcs estados de la actividad secretora. Un concepto vcrdadero de la naturaleza de 10s elementos nucleares depende en sumo grado de la interpretacih de la accidn de 10s fijadores. El autor estudia con considerable detalle 10s grjnulos citopllismicos, las mitocondrins y fibrillas con referen… Show more

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Cited by 47 publications
(2 citation statements)
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“…It is admitted that important aspects of the secretory phenomenon are incompletely understood and, in many respects, unknown; that points of view differ as to what does or does not constitite a secretion product, or even secretory activity versus pathologic degeneration; that it is not altogether evident where the line should be drawn, even for purposes of discussion, between secretory phenomena and those intracellular processes having to do with cell maintenance and differentiation phenomena of the cellular or protoplasmic units. Nevertheless, with a few doubtful exceptions as pointed out by Bowen (1929) and Dawson (1942) and others, a few tangible, morphologically discernible, and physiologically demonstrable features have evolved which are characteristic of secretory activity in its entirety as it is manifest by exocrine glands and the majority of another (Bowen, 1929;Dawson, 1942;Severinghaus, 1933;Saguchi, 1920;Hirsch, 1939;Hibbard, 1945;Gatenby, 1931;Lavdovsky, 1877;Caspersson, 1947). While no one would deny that secretory activity must depend upon the combined integrated functioning of all parts of the cell; e.g., nucleus, nucleoli, mitochondria, golgi complex, cytoplasmic ground substance, protoplasmic membranes, efc., it has not been possible, so far, to define clearly the particular role of each cellular component, if any, in the various phases of the secretory phenomenon.…”
Section: The Morphologic Characteristics Of Secretory Activity I Nmentioning
confidence: 99%
“…It is admitted that important aspects of the secretory phenomenon are incompletely understood and, in many respects, unknown; that points of view differ as to what does or does not constitite a secretion product, or even secretory activity versus pathologic degeneration; that it is not altogether evident where the line should be drawn, even for purposes of discussion, between secretory phenomena and those intracellular processes having to do with cell maintenance and differentiation phenomena of the cellular or protoplasmic units. Nevertheless, with a few doubtful exceptions as pointed out by Bowen (1929) and Dawson (1942) and others, a few tangible, morphologically discernible, and physiologically demonstrable features have evolved which are characteristic of secretory activity in its entirety as it is manifest by exocrine glands and the majority of another (Bowen, 1929;Dawson, 1942;Severinghaus, 1933;Saguchi, 1920;Hirsch, 1939;Hibbard, 1945;Gatenby, 1931;Lavdovsky, 1877;Caspersson, 1947). While no one would deny that secretory activity must depend upon the combined integrated functioning of all parts of the cell; e.g., nucleus, nucleoli, mitochondria, golgi complex, cytoplasmic ground substance, protoplasmic membranes, efc., it has not been possible, so far, to define clearly the particular role of each cellular component, if any, in the various phases of the secretory phenomenon.…”
Section: The Morphologic Characteristics Of Secretory Activity I Nmentioning
confidence: 99%
“…19 Ausser diesen Autoren glauben viele Autoren, dass die kleinsten sichtbaren Anlagen der 'SekretkOrner von besonderen prdexistenten, histologisch bestim.mt geformtem Gebilde der Zelle abstammen. Hoven (1910Hoven ( , 1912 Diese Auffassung wird von Schultze (1911), Champy (1911), Arnold (1912), Maximow (1616), Takagi (1920), Saguchi (1920) usw. unterstiitzt.…”
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