Abstract:The most adequate media for Streptomyces hyalurolyticus to produce Hyaluronidase (HAase) were investigated. This Streptomyces secreted maximum yield of HAase, 46 TRU/ml, as a constitutive enzyme after 40 hr submerged cultivation in 101 culture fluid of jar fermentor, from which the enzyme was purified routinely by solvent precipitation,
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