Studies on the Toxicity of the Autoxidized Oils. VI.

Mechanisms of isomerization and oxidation in heated trilinolein by DFT method

“…2,[11][12][13][14] Among these decomposition products aldehydes are dominant and are highly toxic and reactive. [15][16][17][18] Hexanal is an aldehyde which is closely linked to potential immunotoxic effects on the human pulmonary system or pulmonary inammatory/immune responses to the respiratory system. 19 There is a close link between women's lungs, 2,4decadienal and the development of adenocarcinoma, due to their frequent exposure to oil smoke during deep-frying processes.…”

Formation of Fluorescent Products in the Reaction of Adenine and Other Bases with Secondary Oxidation Products of Methyl Linoleate Hydroperoxides

“…Secondary lipid oxidation products have been suggested to be more toxic to animals than monohydroperoxides. 7,8) These lipid oxidation products are known to react with a wide variety of amino groups in biological systems, including amino acids and proteins,9,10) nitrogen bases of phospholipids,ll) and DNA, 12) to form fluorescent pigments, which have been related to aging or tissue injuries. 4 ) aldehyde groups and amino acids has been proposed by Tappel's group.13) In contrast, Kikugawa et al 16 • 17 ) reported that malonaldehyde reacts with primary amines to afford another type of fluorescent compound, 1,4-dihydropyridine-3,5-dicarbaldehyde.…”

Effect of autoxidized oil on carp.

“…Toxi city of hydroxyalkanals and alkenals were also observed. 8) Several workers have reported the toxic effect of autoxidized oil on fish. Among them, WArA NABE et al [9][10][11][12] investigated the subject in detail and reported that autoxidized saury oil caused poor growth, high mortality and characteristic muscular dystrophy called "Sekoke" disease of carp.…”