Studies on the Velocity of Blood Flow

Studies on the Velocity of Blood Flow

“…Some patients complained of weakness and fatigue but these factors, according to Peabody and Sturgis (25), are not important in causing a reduction of the vital capacity of the lungs. We are unable to explain this lowering in the vital capacity, though it may well be related to the presence of an increased amount of blood in the lungs (14,6), coincident with an increased rate of blood flow. The solid dots refer to measurements in patients with "'primary" anemia, the circles, to measurements in patients with anemia secondary to diseases other than carcinoma.…”

“…The variations may well be due to small differences in the basal metabolic rate, some investigators having found normal values, others an increase (15). Previous studies have indeed shown that the pulmonary circulation time may be affected by the metabolic rate (6,7).…”

“…This serves to explain why symptoms such as dyspnea, signs of congestive failure, peripheral edema, weakness and cyanosis are frequently more pronounced in patients with carcinoma than one would expect on the basis simply of anemia, malnutrition or toxicity. 6. In contrast to the unusually rapid blood flow in patients with anemia, two subjects with polycythemia vera showed definite retarda-VELOCITY OF BLOOD FLOW tion of the blood flow below the average normal; the characteristics of the blood in this condition are the reverse of those present in anemia and the circulatory adjustment is correspondingly altered.…”

The Blood Volume in Hyperthyroidism

“…In spite of the widely different methods employed, all investigators with the single exception of Rabinowitch and Bazin (9) have come to the same conclusion as that reached by Plesch. Blumgart, Gargill and Gilligan (13) studied 13 thyrotoxic patients and showed that the 475 speed of blood flow through the lungs was much faster than the avefage normal speed of flow. The velocity of the venous blood flow from the arm to the heart was likewise greatly enhanced.…”

Studies on the Velocity of Blood Flow

“…The present study undertakes the correlation of the clinical manifestations of myxedema with changes in the velocity of blood flow, basal metabolic rate, pulse rate, plasma volume, venous and arterial pressures, respiratory minute volume and vital capacity of the lungs. The same methods were employed as in the preceding study of thyrotoxicosis (1). RESULTS Sixteen series of measurements were made in seven consecutive patients with the classical clinical manifestations of spontaneously occurring myxedema (table 1).…”