Studies on Tinospora cordifolia monosugars and correlation analysis of uronic acids by spectrophotometric methods and GLC

Kumar, Vineet; Nagar, Shipra

doi:10.1016/j.carbpol.2013.07.083

Cited by 17 publications

(9 citation statements)

References 26 publications

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“…The chief phytoconstituents of Tinospora cordifolia include berberine, tembetarine, palmatine, magnoflorine, tinosporone, tinosporaside, tinocordifolioside, tinosporic acid, cordifolisides A to E, syringen, β and ∂ ‐sitosterol. It has been reported to show varied pharmacological actions such as anti‐ischaemic, hypolipidemic, blood purifier, cardiotonic, diuretic, anti‐inflammatory, antispasmodic (Kumar & Nagar, ). The reported amount of berberine present in Tinospora cordifolia is about 0.319% w/w on dry weight basis (Srinivasan, Unnikrishnan, Shree, & Balachandran, ).…”

Section: Herbs With An Established Potential For Hdi With Drugs Of Otmentioning

confidence: 99%

Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies

Shaikh

Thomas

Chitlange

2020

Phytotherapy Research

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About 70% of the world population is currently using medicinal herbs as complementary or alternative medicine, which is increasing at a tremendous pace in both developed and developing countries in the last two decades (World Health Organization Medicines Strategy 2002–2005). This increase in consumer demand of medicinal herbs continues despite the rarity of scientific data to establish their safety and efficacy profile. Its popularity is also attributed to several factors, including easy availability, cost effectiveness leading to better purchasing power and general perception that they are safe. Herbs are often administered concomitantly with therapeutic drugs for the treatment of major ailments, raising the potential for herb–drug interactions (HDIs). The major pathways postulated for HDIs involves the cytochrome P450 (CYP450)‐mediated inhibition or induction and transport and efflux proteins. In our review, we highlight frequently used herbal medicines for the treatment of cardiovascular disorders (CVD), their established HDIs studied using in vitro tools and in vivo pharmacokinetic and pharmacodynamic assays and case reports. Herbs have been divided into different sections on the basis of availability of HDI data in relevance to cardiovascular drugs: herbs reported to interact with cardiac drugs, herbs yet to be reported for interaction with drugs of any class and herbs reported to interact with drugs of other therapeutic category but not with cardiac drugs. The amount of active phytoconstituents present in the selected herbs and their extent of bioavailability are also mentioned. This review can serve as a quick reference database for physicians and health care professionals involved in CVD treatment, aimed at maximizing clinical outcomes with reduction in adverse and toxic effects.

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Section: Herbs With An Established Potential For Hdi With Drugs Of Otmentioning

confidence: 99%

Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies

Shaikh

Thomas

Chitlange

2020

Phytotherapy Research

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“…Conventionally, colorimetric methods using different chromogens including carbazole, 3-phenylphenol and 3,5-dimethylphenol (DMP) are most commonly used methods explored for uronic acid estimation in polysaccharides but these methods counter numerous difficulties when neutral sugars are present in substantial amount (41). GC analysis despite time consuming for derivatization procedure remains the finest method for precise estimation of uronic acids (41,42). The derivatives including acetates (43), TMS derivatives (22,44), oximes derivatives (45), and alditol acetates (26) have been used for the analysis of sugar acids.…”

Section: Sugar Acidsmentioning

confidence: 99%

Quality control of sweet medicines based on gas chromatography-mass spectrometry

Zhao

et al. 2015

DD&T

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“…The mechanism of spectrometric method and chromatographic method is that hydrolysis products such as monosaccharides or galacturonic acid of pectin in acidic conditions could be measured by instruments [9,10]. Though they possess the advantages of high resolution and fast analysis speed, some complex pretreatment of samples is required [11], and other components such as cellulose and hemicellulose can also be hydrolyzed causing higher absorbance [12]. Most importantly, these methods must decompose pectin, therefore making it hard to retain it, so it is only slightly applied in some fields.…”

Section: Introductionmentioning

confidence: 99%

A New Method for Determination of Pectin Content Using Spectrophotometry

Wang

Chen

et al. 2021

Polymers

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The study aimed at developing a new spectrophotometric method for determining the pectin content. Take commercial pectin as an example, and the method is based on the reaction of copper ions with pectin to produce copper pectate. The spectrophotometer was used to measure the remaining content of copper ions so as to calculate the pectin content. This method eliminated the weight step and avoided the error associated with it. Effects of reaction time, temperature, and pH on absorbance were also studied. Additionally, the accuracy of this method was verified. It indicated excellent repeatability and accuracy with the relative standard deviation of 2.09%. In addition, three different plant types were used to demonstrate the reliability of the method. To summarize, this method can be widely used for the determination of pectin content in many materials.

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Studies on Tinospora cordifolia monosugars and correlation analysis of uronic acids by spectrophotometric methods and GLC

Cited by 17 publications

References 26 publications

Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies

Herb–drug interaction studies of herbs used in treatment of cardiovascular disorders—A narrative review of preclinical and clinical studies

Quality control of sweet medicines based on gas chromatography-mass spectrometry

A New Method for Determination of Pectin Content Using Spectrophotometry

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