This prospective and descriptive study was conducted at the department of General Surgery, A total 100 patients mean age of presentation was 35.23±12.32 years, mean duration of operation was 40.32± 14.96 minutes. Age group of 21-40 (67%) was highly effected. Females (66%) were maximum affected than males(34%). The most common mode of presentation being pain (43%), followed by Nausea(21%), Dyspepsia (17%), Pain + Jaundice(10%) and Pain + Nausea(9%) in decreasing order, patients with palpable gallbladder(16%) had more difficulty in operation. USG thickness >3mm (42%) and single stone(19%) in ultrasound of gallbladder had difficulties in operation with duration of operation >40min. Sensitivity, Specificity, Positive predictive value, Negative predictive value and Diagnostic accuracy of detection of stone in ultrasound were 100%, 98.83%, 93.94%, 100% and 99% respectively. All specimens after operation sent for histopathological examination and found Chronic cholecystitis (74%) is maximum followed by Acutecholecystitis(23%) and Mucocele of gallbladder(3%). Out of 100 laparoscopic cholecystectomy, 5cases were converted to open-cholecystectomy due toadhesions around gallbladder which would not be detected in ultrasound.