Study of a new electromagnetic sensor for glycaemia measurement:<i>in vitro</i>results on blood pig

Gourzi, Mohamed; Rouane, Amar; Guelaz, Rachid; Nadi, Mustapha; Jaspard, Frédéric

doi:10.1080/0309190031000098845

Cited by 18 publications

(11 citation statements)

References 8 publications

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“…Thus, it is difficult to conclude whether their sensor was able to detect the conductivity variations directly determined by glucose in a solution, and hence a direct comparison with our results is not possible. In fact, the presence of cellular components exposes a fluid sample to specific dispersion phenomena, that were probably present in the experiments performed in studies [19,20], but not in our experiments. In any case, in both static and dynamic conditions, in the analyzed blood samples they found significant variations in the sensor output voltage in relation to variations in blood glucose concentration, and the relationships were almost linear, in agreement with our results.…”

Section: Discussionmentioning

confidence: 66%

“…The first and, to our knowledge, only studies where an electromagnetic approach was proposed for possible non-invasive measurement of glucose concentration values were those reported in [19,20]. Like in our study, the authors in [19,20] performed an in vitro investigation of their electromagnetic sensor; they performed their experiments on animal blood, but not on solutions lacking cellular components.…”

Section: Discussionmentioning

confidence: 80%

“…Like in our study, the authors in [19,20] performed an in vitro investigation of their electromagnetic sensor; they performed their experiments on animal blood, but not on solutions lacking cellular components. Thus, it is difficult to conclude whether their sensor was able to detect the conductivity variations directly determined by glucose in a solution, and hence a direct comparison with our results is not possible.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

A Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions

Tura¹,

Sbrignadello²,

Cianciavicchia³

et al. 2010

Sensors

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In recent years there has been considerable interest in the study of glucose-induced dielectric property variations of human tissues as a possible approach for non-invasive glycaemia monitoring. We have developed an electromagnetic sensor, and we tested in vitro its ability to estimate variations in glucose concentration of different solutions with similarities to blood (sodium chloride and Ringer-lactate solutions), differing though in the lack of any cellular components. The sensor was able to detect the effect of glucose variations over a wide range of concentrations (∼78–5,000 mg/dL), with a sensitivity of ∼0.22 mV/(mg/dL). Our proposed system may thus be useful in a new approach for non-invasive and non-contact glucose monitoring.

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Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

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A Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions

Tura¹,

Sbrignadello²,

Cianciavicchia³

et al. 2010

Sensors

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“…In [24] the dielectric properties of blood with glucose varying in a wide range were studied by a sensor made of two induction coils coupled through two glass tubes containing porcine blood. The ratio between the voltages at the two inductors varied for different glucose values.…”

mentioning

confidence: 99%

Impedance spectroscopy of solutions at physiological glucose concentrations

Tura¹,

Sbrignadello²,

Barison³

et al. 2007

Biophysical Chemistry

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Impedance spectroscopy has been proposed as possible approach for non-invasive glycaemia monitoring. However, few quantitative data are reported about impedance variations related to glucose concentration variations, especially below the MHz band. Furthermore, it is not clear whether glucose directly affects the impedance parameters or only indirectly by inducing biochemical phenomena. We investigated the impedance variations in glucosewater, glucose-sodium chloride, and glucose-blood samples, for increasing glucose values (up to 300 mg/dl). In all the frequency range (0.1-10 7 Hz) glucose-water samples showed impedance modulus increases for increasing glucose values (up to 135%). In blood and sodium chloride samples the impedance modulus showed only slight variations (2% and 1.4%), but again in wide frequency ranges. Therefore: i) glucose directly affects the impedance parameters of solutions; ii) effects are more relevant at frequencies below the MHz band; iii) the influence on the impedance is decreased in high conductivity solutions, but still clearly present.

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“…С помощью электромагнитной спектроскопии можно определить концентрацию глюкозы, измеряя силу электромагнитного взаимодействия двух индук-торов, которая зависит от диэлектрической проница-емости среды, а последняя в свою очередь -от ло-кальной концентрации глюкозы [35].…”

Section: другие подходыunclassified

Continuous glucose monitoring technologies: state of the art and future perspectives in view of artificial pancreas

Владимирович¹,

Иванович²,

Андреевна³

et al. 2015

Probl Endokrinol (Mosk)

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Continuous glucose monitoring (CGM) - a relatively new and rapidly developing technology of optimization glycemic control in patients with diabetes. The efficiency of the use of CGM for improving glycemic level in many clinical situations (asymptomatic hypoglycemia, high blood glucose variability, etc.). In the long term, CGM treated as a mandatory component of the «artificial pancreas» - an insulin pump with a closed-loop control infusion of insulin depending on the concentration of glucose in the blood. However, the modern technology such as CGM could not be used, as a data source to control closed-loop insulin pump (artificial pancreas), because of the significant limitations and lack of precision. In further development of technologies CGM, obviously, will address three main objectives: increased service life of sensors for the detection of glucose, improving the accuracy of measurement results and ease of use for patients. This article describes the main technological solutions of modern devices for CGM and promising directions for further developments in this field, their potential advantages and disadvantages, including in the light of the prospects for further integrating them into an «artificial pancreas».

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Study of a new electromagnetic sensor for glycaemia measurement:in vitroresults on blood pig

Cited by 18 publications

References 8 publications

A Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions

A Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions

Impedance spectroscopy of solutions at physiological glucose concentrations

Continuous glucose monitoring technologies: state of the art and future perspectives in view of artificial pancreas

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