Study of acoustic nonlinearity parameter imaging methods in reflection mode for biological tissues

Abstract

Three novel methods for acoustic nonlinearity parameter B/A imaging in reflection mode are developed in this paper. They are: (1) the acoustic nonlinearity parameter B/A tomography by detecting reflective second harmonic wave, (2) the B/A tomography in reflection mode via the measurement of the difference frequency wave generated by a parametric array, and (3) the C-scan imaging of B/A via the measurement of the echo second-harmonic signal. A theoretical analysis and the experimental imaging of normal and pathological biological tissues by using these methods are also present and discussed. Results show that using the acoustic nonlinearity parameter imaging we can more easily distinguish the diseased tissue from the normal one than using the linear acoustic parameters.

Noninvasive Estimation of Temperature Elevations in Biological Tissues Using Acoustic Nonlinearity Parameter Imaging

“…It has been reported that, compared with the linear ultrasonic parameters, the acoustic nonlinearity parameter B/A can provide more information on the state of the tissues and may become a novel parameter for biological tissue characterization (Bjørnø 1986;Gong et al 1993;Law et al 1985;Muir and Carstensen 1980;Sehgal et al 1986;Yoshizumi et al 1987). To explore the potential applications of this parameter in ultrasound imaging, several imaging techniques have been proposed (Cain 1986;Gong et al 2004;Ichida et al 1983Ichida et al , 1984Nakagawa et al 1986;Zhang et al 1996Zhang et al , 1999.…”

Nonlinear Ultrasonic Phased Array Imaging

“…The lack of progress in this field is primarily due to the difficulty in spatially isolating the source of wave distortion due to acoustic nonlinearity since the wave is not accessible by measurement systems at all points. Most measurements of acoustic nonlinearity have, therefore, been limited to spatially averaged values [8] or implicit localization through exhaustive tomographical methods [9][10][11]. Few explicit techniques have been proposed for the imaging of acoustic nonlinearity.…”

Principle and Performance of Magnetically Induced Magnetoacoustic Tomography for Tissues with Cone Shaped Transducer

“…One is "generated" by the conductivity 1 σ of the outer medium to form a quasi-uniform homogeneous object while the other is "generated" by the conductivity discrepancy σ Δ only within the inner medium. So we can separate the multilayer object into layers to calculate the generated acoustic pressures of each medium separately.…”

“…Each image technique can display one of the properties of tissues, such as attenuation coefficient, scattering coefficient, electrical impedance, acoustic impedance etc. For the past decades, numerous of effects have been made to find new ways to detect the new characteristics for novel imaging techniques and to improve the efficiency and the resolution of the current imaging techniques [1]. As we know when a sound wave transmits through an object, there are acoustic reflections at the medium boundaries with different acoustic impedance, which determines the reflection coefficient.…”