1998
DOI: 10.1016/s0378-8741(98)00030-0
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Study of an Argentine Mistletoe, the hemiparasite Ligaria cuneifolia (R. et P.) Tiegh. (Loranthaceae)

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Cited by 46 publications
(39 citation statements)
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“…), which is widely used in Argentina as a substitute for European mistletoe, an inhibitory effect was observed at high concentrations (10 µg/mL and 100 µg/mL) on the proliferation of splenocytes stimulated with ConA or LPS. An inhibitory effect was also observed on the proliferation of murine leukemia cells (Fernandez et al, 1998). Collectively, these data may provide new clinical perspectives in future mistletoe therapy and support the administration of local inducers of apoptosis that induce an inflammatory response.…”
Section: Discussionmentioning
confidence: 54%
“…), which is widely used in Argentina as a substitute for European mistletoe, an inhibitory effect was observed at high concentrations (10 µg/mL and 100 µg/mL) on the proliferation of splenocytes stimulated with ConA or LPS. An inhibitory effect was also observed on the proliferation of murine leukemia cells (Fernandez et al, 1998). Collectively, these data may provide new clinical perspectives in future mistletoe therapy and support the administration of local inducers of apoptosis that induce an inflammatory response.…”
Section: Discussionmentioning
confidence: 54%
“…Single cells were prepared by mincing spleen fragments and pressing them through a stainless 200-mesh screen in the RPMI complete medium (Fernandez et al, 1998). The RPMI-1640 complete medium was supplemented with 10% fetal calf serum, 2 mM L-glutamine, 50 μM β-mercaptoethanol, penicillin (100 U/ml) and streptomycin (100 μg/ml).…”
Section: Cell Line and Culturementioning
confidence: 99%
“…Neste sentido, alguns ensaios têm sido feitos, bem como a identificação de constituintes químicos com potencial farmacológico para comprovar estas propriedades (SOBERÓN et al, 2010a). Seus principais constituintes descritos até o presente momento são os compostos polifenólicos, que envolvem flavonóides (rutina, nicotiflorina, hiperosídeo e isoquercetrina), taninos condensados, proantocianidinas e catequinas (catequina, epicatequina e catequina-4-β-ol) (FERNANDEZ et al, 1998;DAUD;HABIB;RIERA, 2006;RICCO et al, 2008;SOBERÓN et al, 2010b), além de um raro fenilbutanóide glicosilado chamado tripodantosídeo (SOBERÓN et al, 2010b) entre outros metabólitos, tais como taninos, lignanas e monoterpenos glicosilados, além de lectinas, viscotoxinas, proteínas, peptídeos, oligossacarídeos e alcalóides, que vem despertando a curiosidade de pesquisadores por investigações fitoquímicas devido a esta diversidade de compostos (PISSINATE, 2006).…”
Section: Fundamentação Teóricaunclassified