Study of biochemical parameters of atherosclerosis male patients in tertiary care hospital of Rewa, Madhya Pradesh, India

Abstract

Background: Atherosclerosis is characterized by intimal lesions called atheromas or atheromatous or fibro fatty plaques which protrude into and obstruct vascular lumens and weaken the underlying media. Global in distribution, atherosclerosis over whelming contributes to more mortality approximately half of all deaths and serious morbidity in the Western World than any other disorder. The atherosclerotic plaque is a lumpy thickening of the arterial wall, narrows the passage way and initiates the formation of a blood clot that can ultimately close down a critical artery. The objective of the study was to comparative biochemical parameters in different age group of atherosclerosis male patients.Methods: It was a prospective study, conducted in department of medicine of tertiary care hospital at Rewa. 30 atherosclerotic patients were selected for this study on the basis of inclusion and exclusion criteria, Biochemical testing was done for all patients and data of biochemical parameters were reported as the Mean±SD. Results were performed by the unpaired student’s t-test.Results: Total 30 atherosclerosis male patients and 27 normal healthy male volunteers were enrolled for the study. Biochemical parameters of both of this group were compared with t-test and p-value was found significant.Conclusions: Risk factors such as elevations in body mass index, systolic blood pressure, serum LDL cholesterol, triglyceride concentration and cigarette smoking are significantly related to the extent of atherosclerotic lesions.