Study of cardiac structure and function assessed by echocardiography in patients older than 100 years

Echocardiographic Features of Longevity: A Cross-Sectional Study of Centenarians

“…The most prevalent cardiovascular co-morbidity in the present cohort was hypertension, which was observed in 77% of patients, and is similar to prior registry data [ 7 - 10 ]. Aging is associated with vascular changes at the level of the arterial wall media as well as the endothelium, which reduces arterial distensibility and promotes increased vascular stiffness [ 18 ].…”

“…Congestive heart failure is one of the leading causes of death in the centenarian population, with the majority of patients having a preserved LV ejection fraction (HFpEF) [ 7 , 8 , 10 ]. As a preserved LVEF >50% was present in 85% of the cohort patients, it can be inferred that HFpEF was the clinical paradigm most prevalent among the 42% who had a history of congestive heart failure in the present study.…”

“…This imparts a significant benefit in the diagnosis and treatment of cardiovascular disorders across age groups. Nevertheless, cardiac structural and physiologic changes have not been studied in centenarians to the extent that they have in younger populations, and published data have generally been limited by small sample sizes and differing methodologies [7][8][9][10]. This investigation aimed to describe the echocardiographic characteristics of a cohort of centenarians at a tertiary referral center and to compare the findings between male and female patients.…”