Study of cardiovascular diseases in hospitalized AECOPD patients

El-Shabrawy, Mohamed; Eldamanhory, Ahmed Said

doi:10.1016/j.ejcdt.2016.08.008

Cited by 6 publications

(6 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…24 In our study, we also found that patients with COPD and CVD suffered two or more exacerbation per year. They had significantly higher need for mechanical ventilation (20.4% versus 7.7%) and longer duration of hospital stay (9.12 1.06 days versus 6.89±1.32 days) compared to COPD patients without CVD reported by Garcia et al, ElShabrawy and Eldamanhory and Wang Y et al 1,25,26 In agreement with Cataluña et al authors also found significantly higher mortality in COPD with CVD group (11.7% versus 3.7%) compared to COPD without CVD group. 27 This higher incidence of mortality is because of higher incidence of arrhythmia, AMI, and CHF in CVD patients.…”

Section: Discussionmentioning

confidence: 74%

“…Similar to present results, Almagro et al, De Torres et al and El-Shabrawy and Eldamanhory also found higher preponderance of CVD in males COPD patients compared to females COPD patients. 1,20,21 This may be explained by the difference in prevalence of smoking in males and females and the protective effect of estrogen in females.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have reported 16.7% -23.9% incidence of CCF. 1,19 It is proposed that coexistence of COPD in patients with IHD increases the risk of myocardial infarction. Myocardial infarction may result in left heart failure that in long-term leads to RV dysfunction resulting in CCF.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 Cardiovascular disorders i.e. coronary artery disease (CAD), congestive cardiac failure (CCF), pulmonary artery hypertension (PAH), systemic hypertension (HTN) and peripheral vascular disease (PVD) are important comorbidities associated with COPD.…”

Section: Introductionmentioning

confidence: 99%

“…4 Acute insults either infectious (viral or bacterial), or environmental in nature in patients with COPD results in the clinical syndrome of acute exacerbation of COPD (AECOPD). 1 AECOPD constitutes a major cause of morbidity and mortality in patients with COPD with a 50% mortality at 3.6 years, 75% mortality at 7.7 years, and 96% mortality at 17 years following the index hospitalization for AECOPD. 5 Not infrequently, there is a cardiovascular trigger underlying this clinical presentation and this remains a challenge to identify.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Prevalence of cardiovascular diseases in patients hospitalized for acute exacerbation of COPD: prospective observational study

et al. 2018

View full text Add to dashboard Cite

Background: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has considerable cardiovascular risk. Various cardiovascular diseases are common during exacerbations. Both diseases share several similarities such as older age of the patient, smoking as a common risk factor and symptoms of exertional dyspnea. Knowledge regarding the magnitude of underlying cardiovascular diseases during AECOPD is limited. Authors performed this study to assess the presence of different associated cardiovascular diseases (CVDs) in patients hospitalized for AECOPD and its effect on the outcome.Methods: It was a prospective observational study involving 436 patients of AECOPD divided to Group 1 (AECOPD with CVD- 137 (31.4%) patients) and Group 2 (AECOPD without CVD 299 (68.6%) patients). All the patients were subjected to full history taking, clinical examination, chest X-ray, spirometry, ECG and echocardiography.Results: COPD patients in exacerbation with CVD, were significantly more likely to have longer duration of hospital stay (p < 0.0001), high CRP level (p<0.001), more frequent mechanical ventilations (p < 0.001), two or more exacerbations per year (p <0.0001) and the mortality was (p<0.0001). Also, they have GOLD grade III/IV severe (43.5%) and very severe (19.5%) air flow limitation. The high percentage of them had (64.8%) pulmonary hypertension, (37.3%) systemic arterial hypertension, (31.5%) arrhythmia, (27.8%) ischemic heart diseases and (21.3%) heart failure.Conclusions: The prevalence of cardiovascular diseases (CVD) in patients hospitalized for COPD was high. Age, sex and CVD trends, as well as life style changes, should be considered when prevention and control strategies are formulated.

show abstract

Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Prevalence of cardiovascular diseases in patients hospitalized for acute exacerbation of COPD: prospective observational study

et al. 2018

View full text Add to dashboard Cite

show abstract

Chronic Obstructive Pulmonary Disease with Incidence of Heart Failure and Its Influencing Factors

Agus

Adrianison

Siswanty³

et al. 2022

View full text Add to dashboard Cite

Introduction: Chronic obstructive pulmonary disease (COPD) is often associated with cardiovascular disease because it has the same risk factors as smoking. One of the cardiovascular complications in COPD is heart failure. Echocardiography examination is a tool to evaluate changes of the heart both anatomically and functionally. This study aimed to determine the relationship between COPD and heart failure by echocardiography examination in stable COPD patients.Methods: This was a descriptive-analytic study using a cross-sectional design for COPD patients who visited the Lung Polyclinic of Arifin Achmad Hospital, Pekanbaru, Riau, which was conducted from November 2020 to March 2021. Subjects who met the inclusion criteria were examined by spirometry, chest X-rays, and echocardiography.Results: In this study, there were 66 stable COPD subjects. It was found that 15.2% of subjects had right heart failure based on the tricuspid annular plain systolic excursion (TAPSE) assessment and 7.6% of the subjects had left heart failure based on the left ventricular ejection fraction (LVEF) value. Right ventricular dilatation (p = 0.000), right ventricular dysfunction (p = 0.005), and increased probability of pulmonary hypertension (PH) (p = 0.000) were significantly associated with a decrease in the first second forced expiratory volume (FEV1).Conclusion: The severity of COPD with FEV1 <50% had a significant relationship with dilatation, dysfunction of right ventricular, and increased the probability of incidence of PH based on parameters tricuspid regurgitation (TR). A history of exacerbations ≥2 times in a year caused right ventricular dilatation, decreased right ventricular function, and increased the probability of PH.

show abstract

The Incidence and Prevalence of Pulmonary Hypertension in the COPD Population: A Systematic Review and Meta-Analysis

Zhang¹,

Liu²,

Zhao³

et al. 2022

COPD

View full text Add to dashboard Cite

Purpose Chronic obstructive pulmonary disease (COPD)-related pulmonary hypertension (PH) is one of the most common comorbidities of COPD, and often leads to a worse prognosis. Although the estimated prevalence and risk factors of COPD-related PH have been widely reported, these results have not been well integrated. This study aimed to review the worldwide incidence and prevalence of COPD-related PH and explore possible factors affecting its prevalence. Patients and Methods We searched four electronic databases (Web of Science, Embase, Cochrane, and MEDLINE) to identify all observational studies on the prevalence of COPD-related PH from database creation until July 20, 2021. Eligibility screening, quality assessment, and data extraction of the retrieved studies were independently conducted by two reviewers. Meta-analyses were performed to determine the prevalence of PH in the COPD population. Random-effects meta-regression model analyses were conducted to investigate the sources of heterogeneity. Results Altogether, 38 articles were included in the meta-analyses. The pooled prevalence was 39.2% (95% CI: 34.0–44.4, I 2 = 97.6%) for COPD-related PH. Subgroup analyses showed that the prevalence of PH increased with COPD severity, where the majority (30.2%) had mild PH and the minority had severe PH (7.2%). Furthermore, we found a significant regional difference in the prevalence of COPD-related PH ( P = 0.000), which was the highest in Africa (64.0%) and the lowest in Europe (30.4%). However, stratified studies on other factors involving mean age, sex, enrolment time, participant recruitment settings, and PH diagnostic methods showed no significant differences in prevalence ( P >0.05). Conclusion The global incidence of PH in the COPD population is very high, and there are significant regional and international variations. Patients with COPD should be screened for PH and contributing risk factors to reduce the burden on individuals and society.

show abstract

Study of cardiovascular diseases in hospitalized AECOPD patients

Cited by 6 publications

References 58 publications

Prevalence of cardiovascular diseases in patients hospitalized for acute exacerbation of COPD: prospective observational study

Prevalence of cardiovascular diseases in patients hospitalized for acute exacerbation of COPD: prospective observational study

Chronic Obstructive Pulmonary Disease with Incidence of Heart Failure and Its Influencing Factors

The Incidence and Prevalence of Pulmonary Hypertension in the COPD Population: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About