Study of Compliance, Pattern of Treatment Interruption and Adverse Events Reported by Anaemic Pregnant Women Receiving the Parenteral Iron Sucrose Therapy

Abstract

Background: In spite of many efforts by the government since independence anaemia in pregnant women has shown resistance to improvement. Aim: The main aim was to study the compliance of parenteral iron sucrose therapy in pregnant woman along with an additional objective which was to study the pattern of treatment interruption and adverse events observed by them. Methods: This study was conducted by the Department of Community Medicine in the rural and urban field practice area of district Nuh. A list of three hundred and eighty four anaemic pregnant females put on IVIS therapy, fetched from the health centre and relevant details were documented. Result: Out of total of 384 study participants, 291 (75.8%) were compliant with IVIS therapy i.e., they received all four doses. Out of total 93 either non-compliant or partially compliant subjects, most of them (51.6%, n=48) missed 3 doses whereas 22 participants (23.7%) missed 2 doses of the IVIS therapy. Ten study participants (10.7%) showed non-compliance to the therapy. Multigravida subjects were either non or partial compliant compared to primigravida. The three most common adverse events recorded at the time of infusion of 1st dose of IVIS therapy were swelling at injection site, pruritus, and muscle pain or joint pain experienced by 32 (8.3%), 17 (4.4%) and 16 (4.2%) study participants respectively. Conclusion: IVIS therapy is relatively safe therapy and well tolerated by anaemic pregnant females when given as slow infusion. Multigravida subjects were either non or partial compliant compared to primigravida females for IVIS therapy.