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Many scientific studies indicated that there is no close correlation between the malnutrition and weight gain (obesity) with iron deficiency, which leads to anemia. This study was designed to find the nature of the relationship between fat accumulations in adults with anemia.This study and tests were conducted in Mosul/Iraq, and random samples werecollected from adults in two clinical analysis laboratories accredited by the Department of Health. The samples were taken after fasting for 14 consecutive hours to check out the level of cholesterol, LDL, the lipase enzyme, and some chemical elements such as iron and copper, as well as measuring the HB% percentage. The results were analyzed statistically based on the t-test using SPSS statistical program, and a value of p<0.05 was considered a significant value within the results.The ages of the people targeted in this investigation were between (18-50) years, and after collecting the test results and analyzing them statistically, the samples were divided into three groups based on the severity of iron deficiency (anemia).The people included in the first group (group A) were with severe anemia, while people in the second group (group B) were for moderate to weak anemia, whereas the third group (group C) designed to be a control group (people who do not have anemia). A comparison was made between group A with the control group C, and the average cholesterolconcentration in group A appeared to be higher than that in group C,-With a significant difference, while the average lipase and LDL levels were slightly, higher in group A compared to the control group, but it was not significant. As for the chemical elements, the average Fe in group A was low, with a significant difference at p<0.05 compared with C, while the copper element, was low in the first group compared to the third group, but it was not significant. The average hemoglobin (Hb) concentration was different between the three mentioned groups, and it was low in the first group compared to the second and third group. There were a significant changes in Hb concentrations between group A compared to group C, while there was no significant difference between group B and group C.The results of the study, after comparing the groups, showed a significant increase in cholesterol concentration in people with all groups of anemia and non-significant differences based on statistical significances in the concentration of lipase and low-density lipoprotein in people with anemia compared to the control group. As in copper element, it was non-significantly low in people with anemia, in contrast, the concentration of iron was low and significant in those with anemia, which is the significant cause of anemia in adults. The study results may agree with previous studies and/ or different from other studies. Therefore, it is suggested that more experiments and research have to be done to find the physiological causes for the extent of the effects of anemia on fat concentrations.
Many scientific studies indicated that there is no close correlation between the malnutrition and weight gain (obesity) with iron deficiency, which leads to anemia. This study was designed to find the nature of the relationship between fat accumulations in adults with anemia.This study and tests were conducted in Mosul/Iraq, and random samples werecollected from adults in two clinical analysis laboratories accredited by the Department of Health. The samples were taken after fasting for 14 consecutive hours to check out the level of cholesterol, LDL, the lipase enzyme, and some chemical elements such as iron and copper, as well as measuring the HB% percentage. The results were analyzed statistically based on the t-test using SPSS statistical program, and a value of p<0.05 was considered a significant value within the results.The ages of the people targeted in this investigation were between (18-50) years, and after collecting the test results and analyzing them statistically, the samples were divided into three groups based on the severity of iron deficiency (anemia).The people included in the first group (group A) were with severe anemia, while people in the second group (group B) were for moderate to weak anemia, whereas the third group (group C) designed to be a control group (people who do not have anemia). A comparison was made between group A with the control group C, and the average cholesterolconcentration in group A appeared to be higher than that in group C,-With a significant difference, while the average lipase and LDL levels were slightly, higher in group A compared to the control group, but it was not significant. As for the chemical elements, the average Fe in group A was low, with a significant difference at p<0.05 compared with C, while the copper element, was low in the first group compared to the third group, but it was not significant. The average hemoglobin (Hb) concentration was different between the three mentioned groups, and it was low in the first group compared to the second and third group. There were a significant changes in Hb concentrations between group A compared to group C, while there was no significant difference between group B and group C.The results of the study, after comparing the groups, showed a significant increase in cholesterol concentration in people with all groups of anemia and non-significant differences based on statistical significances in the concentration of lipase and low-density lipoprotein in people with anemia compared to the control group. As in copper element, it was non-significantly low in people with anemia, in contrast, the concentration of iron was low and significant in those with anemia, which is the significant cause of anemia in adults. The study results may agree with previous studies and/ or different from other studies. Therefore, it is suggested that more experiments and research have to be done to find the physiological causes for the extent of the effects of anemia on fat concentrations.
Background: Iron plays a key role in the regulation of body iron homeostasis and is used as a clinical marker for iron deficiency (ID) and hemochromatosis. The idea that iron dysregulation may contribute to various metabolic diseases, such as obesity, insulin resistance, MetS, and T2DM, is a hot topic of discussion. Aim: The aim of this study is to investigate the relationship insulin resistance, iron status markers, and body weight in a sample of Egyptian population. Methods: A case control study was conducted on 90 subjects with age ranging from 18 to 70 years old from a diabetes outpatient clinic, and they were divided to three groups: Group I, non-obese–non-diabetic as the control group; Group II, obese–non-diabetic; and Group III, obese–diabetic. Results: In our study, there was no statistically significant difference between the three studied groups regarding the different iron parameters. Similarly, we found that neither HOMA-IR nor body weight had a significant correlation with iron status markers. On the contrary, we detected significant positive correlations between the TIBC and the fasting blood glucose, between the serum iron and the LDL, between the TSAT and the systolic blood pressure, and between the HOMA-IR and hematocrit. Conclusion: Our study demonstrated no direct statistical significant relationship between the different iron parameters, obesity, and insulin resistance, either in the diabetic or non-diabetic subjects. This may be due to the complex metabolic dysregulation and the small number of the sample for future investigations.
Background: Various studies have reported a correlation (both positive and negative) between the status of anemia and lipid profile. Studies observed that the lipoproteins levels were significantly lower in anemic patients, and this reduction was proportional to the severity of anemia and not related to the type of anemia. Objectives: To study the lipid profile among the anemia patients and the correlation between the severity of the anemia and lipid subfractions. Materials and Methods: This is a cross-sectional study among 85 subjects with anemia in a Tertiary care hospital, who satisfied the eligibility criteria. After detailed history, clinical examination and blood investigations including blood counts, hemoglobin, and lipid profile were done. Results: The mean hemoglobin (g/dL) among the subjects was 7.86 (±2.03) g/dL ranging from 3 to 11 g/dL. Among the 85 subjects, 35 (41.18%) had dimorphic anemia followed by 21 (24.71%) had microcytic hypochromic anemia, 15 (17.65%) had normocytic hypochromic anemia, and 14 subjects (16.47%) had normocytic normochromic anemia. Body mass index was not significantly associated with the type and severity of anemia. Lipid subfractions were not associated with the type of anemia and significantly decreased with an increase in the severity of anemia. Conclusion: The lipid profile parameters in our study were not associated with type of anemia and significantly decreased with an increase in the severity of anemia.
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