This paper aims to initiate reflections on what an antifragile (Taleb, Anti-fragile. Things that gain from disorder. Penguin Books, London 2012) built environment might look like by furthering the debate on dynamic non-equilibrium resilience, specifically in terms of scale, urban morphology and social life in urban areas. It will do so by presenting a critical review of relevant literature on resilience in the built environment and linking it to what we know so far about the physical (i.e. geographical, morphological and so on) and socio-cultural conditions that have likely limited the spread of COVID-19 while maintaining quality in urban space in early 2020. As the current pandemic is sharpening our understanding of both the link between local and global action and the power encompassed in the exercise of professional and technical knowledge and practice, the paper concludes with (i) speculations on how the current crisis and its management (i.e. lockdown and social distancing measures in public space' use) might lead to radical changes to the way we think of, and design the conditions for, urban public life and sociability; and with (ii) an agenda for further research on what role urban forms and uses play in speeding or slowing viral spread in different contexts. Keywords Resilience • COVID-19 • Antifragility • Urban form • Research agenda At the root of every pandemic is an encounter between a disease-causing microorganism and a human being. But that encounter, along with the events that lead up to it and the events that ensue from it, is shaped by numerous other events taking place at the same time-as well as by the weather, the price of bread and ideas about germs, white men and jinns. The pandemic in its turn affects the price of bread, ideas about germs, white men and jinns-and sometimes even the weather. It is a social phenomenon as much as it is a biological one; it cannot be separated from its historical, geographical and cultural context. Spinney (2017, p.5)