Study of drug prescription pattern in ischemic heart disease patients

Abstract

Background: Drug utilization pattern studies helps to screen, assess and propose appropriate modifications in prescription practices, this would help to make patient care rational and cost effective. Study was intended to analyse the drug prescribing pattern for treatment of Ischemic heart disease using WHO indicators.Methods: This is a cross sectional observational study conducted on ischemic heart disease patients admitted at inpatient department of medicine in a tertiary care teaching hospital. The study consisted of analysis of drug utilization pattern of prescribed drugs.Results: IHD was more commonly seen in males (70.06%) than females (29.94%). IHD was most commonly seen in patients of age group of 61-70 year. Drugs prescribed to patients belong to various therapeutic classes ranging from anti-platelets, anticoagulants, anti-anginal, antithrombin, thrombolytic, hypolipidemics. The most commonly prescribed therapeutic class of drugs was antiplatelet (86.26%) followed by hypolipidemic (82.25%) and ACE inhibitors drugs (46.60%). Average number of drugs per encounter was 7.70. Drugs were prescribed by their generic names were 29.99%. Out of total study group 22.06% patients were prescribed at least one antibiotic. Injections were prescribed only in 1392 (27.86%) out of 4995 drugs. Of total drugs 3270 (65.45%) of drugs were from National List of Essential Medicines-2016 (NLEM -2016) and 2774 (55.53%) drugs prescribed were from WHO-EML-2016.Conclusions: Risk of artery disease increased with increasing age. IHD was more common in males than females. The most commonly prescribed drug classes in Ischemic heart disease were anti-platelet drugs followed by hypolipidemic agents.

Study Regarding Ethical Versus Generic Prescription of Statins

“…So there is almost equal proportion of generic and ethical prescriptions in OPD.Both the groups had a significant reduction in LDL and total cholesterol in our study. Our study results were similar to a study on prescription pattern of drugs in ischemic heart disease by Mahadeo P et al 6 which showed that 1498 (29.99%) drugs were prescribed by with generic names. In study by Nagabushan H et al 7 , drugs prescribed by their generic names were 52.9% which is also similar to present study.…”

Epidemiological study in admitted patients with ischaemic heart disease at a Tertiary Care Hospital in North-Western India

“…In this study, it was seen that IHD was most common in elderly patients. This is similar to the results of the study by Sawant MP et al 18 wherein the majority (59.6 %) of the patients were in the age group of 61-80 years and only 4.6 % of patients were from the age group 21-40. This is also similar to the study by Saju et al 19 wherein the majority (47.4 %) of the patients belonged to the age group of 61-79 years and only 5.2 % of patients were from the age group of 21-39 years.…”

“…In this study, the incidence of IHD was predominant in men (76.3 %). This predominance is similar to the studies by Sawant et al, 18 Panchaksharimath et al 21 and Gaur et al 22 On the contrary, Shankar et al 23 showed that there was a slightly more percentage of woman patients (51.94 %) suffering from IHD. In this study, IHD patients came from different geographical regions of Rajasthan.…”