Study of electrochemical behavior of escitalopram oxalate using hanging mercury drop electrode and its determination in human urine and pharmaceuticals

Badulla, Wafa F. S.; Özcan, Saniye; Atkoşar, Zeki; Arlı, Göksel

doi:10.1007/s13738-020-02066-y

Cited by 5 publications

(1 citation statement)

References 28 publications

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“…Very few studies were conducted where only the bare or unmodified working electrode was used for the quantification and detection of SSRIs. These include, boron-doped diamond electrodes, edge-plane graphite electrodes [ 32 ], hanging mercury drop electrodes [ 33 ] and paper-based electrodes [ 34 ].…”

Section: Introductionmentioning

confidence: 99%

Review on Surface-Modified Electrodes for the Enhanced Electrochemical Detection of Selective Serotonin Reuptake Inhibitors (SSRIs)

et al. 2023

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Selective serotonin re-uptake inhibitors (SSRIs) are one of the most commonly prescribed classes of antidepressants used for the treatment of moderate to severe depressive disorder, personality disorders and various phobias. This class of antidepressants was created with improved margins of safety. However, genetic polymorphism may be responsible for the high variability in patients’ responses to treatment, ranging from failure to delayed therapeutic responses to severe adverse effects of treatment. It is crucial that the appropriate amount of SSRI drugs is administered to ensure the optimum therapeutic efficacy and intervention to minimise severe and toxic effects in patients, which may be the result of accidental and deliberate cases of poisoning. Determining SSRI concentration in human fluids and the environment with high sensitivity, specificity and reproducibility, and at a low cost and real-time monitoring, is imperative. Electrochemical sensors with advanced functional materials have drawn the attention of researchers as a result of these advantages over conventional techniques. This review article aims to present functional materials such as polymers, carbon nanomaterials, metal nanomaterials as well as composites for surface modification of electrodes for sensitive detection and quantification of SSRIs, including fluoxetine, citalopram, paroxetine, fluvoxamine and sertraline. Sensor fabrication, sensor/analyte interactions, design rationale and properties of functional material and the electrocatalytic effect of the modified electrode on SSRI detection are discussed.

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Section: Introductionmentioning

confidence: 99%

Review on Surface-Modified Electrodes for the Enhanced Electrochemical Detection of Selective Serotonin Reuptake Inhibitors (SSRIs)

et al. 2023

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Trace level determination of eleven nervous system–active pharmaceutical ingredients by switchable solvent-based liquid-phase microextraction and gas chromatography–mass spectrometry with matrix matching calibration strategy

Bozyiğit

Ayyıldız

Chormey

et al. 2022

Environ Monit Assess

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Up-to-date studies regarding the determination of sertraline by different analytical methods

Alessa,

Algethami

2024

J.Umm Al-Qura Univ. Appll. Sci.

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Sertraline (SER), aka Zoloft, is one of modern antidepressant, it belongs to the selective serotonin reuptake inhibitor class, which functions to raise serotonin levels in the nervous system. SER has both mood-boosting and depressive effects but has bad influence on the gastrointestinal system. The monitor of SER and its major metabolites, desmethyl-SER (DSER) provides useful information that may assist treatments, particularly during adverse reactions or lack of response to the applied therapy. The determination of SER and its metabolites in different samples, like blood, urine, deceased people and water requires various selective, sensitive and reliable analytical methods. These methods would determine and quantify of the whole drug level, as in blood, or unbound form level, as in urine or saliva. The purpose of the current review is to provide a summary of the outcomes of the methods that have been used for the extraction of SER from different sample's types as well as some of the analytical methods that were used for its quantitative analysis. The work targeted the studies of the last decade.

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Study of electrochemical behavior of escitalopram oxalate using hanging mercury drop electrode and its determination in human urine and pharmaceuticals

Cited by 5 publications

References 28 publications

Review on Surface-Modified Electrodes for the Enhanced Electrochemical Detection of Selective Serotonin Reuptake Inhibitors (SSRIs)

Review on Surface-Modified Electrodes for the Enhanced Electrochemical Detection of Selective Serotonin Reuptake Inhibitors (SSRIs)

Trace level determination of eleven nervous system–active pharmaceutical ingredients by switchable solvent-based liquid-phase microextraction and gas chromatography–mass spectrometry with matrix matching calibration strategy

Up-to-date studies regarding the determination of sertraline by different analytical methods

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