Study of Estimation Method for Unsteady Inflow Velocity in Two-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Simulation

Kadowaki, Hiroko; Hayase, Toshiyuki; Funamoto, Kenichi; Taniguchi, Nobuyuki

doi:10.1109/tbme.2015.2461559

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…They were invasive examination methods and can only reflect the stenosis of patients. However, vascular stenosis usually occurs in the late stage of CAD, so the examination for early arteriosclerosis is largely limited (15). Previous studies on CAD show a causal relationship between endothelial function and vascular elasticity (16).…”

Section: Analyses Of Correlations Of the Fmd And Imt With Inflammator...mentioning

confidence: 99%

Correlations of High-frequency Ultrasound Evaluation of Brachial Artery Endothelial Dilatation and Carotid Atherosclerosis with Glucose and Lipid Metabolism, Inflammatory Cytokines, Severity of Coronary Artery Disease and Vascular Endothelial Function in Elderly Patients

Cheng¹,

Sun²,

Yin³

et al. 2022

Cell Mol Biol (Noisy-le-grand)

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The study aimed to explore the correlations of the results of the high-frequency ultrasound evaluation of the brachial artery endothelial dilatation and carotid atherosclerosis with glucose and lipid metabolism, inflammatory cytokines, the severity of coronary artery disease (CAD) and vascular endothelial function in elderly patients. 78 elderly patients with CAD in Beijing Anzhen Hospital were selected. The highfrequency ultrasonography was carried out to observe the flow-mediated dilatation (FMD) and intimamedia thickness (IMT) and to analyze their correlations with inflammatory cytokines [C-reactive protein (CRP) and plasminogen activator inhibitor (PAI-1)], endothelial function [nitric oxide (NO) and endothelin-1 (ET-1)], glycolipid metabolism [high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), triglyceride (TG) and fasting blood glucose (FBG)] and the severity of CAD. FMD, NO and HDL-C: patients with single-vessel CAD> those with double-vessel CAD>those with multivessel CAD. IMT, CRP, PAI-1, FBG, ET-1, TC and TG: patients with single-vesselCAD< those with double-vessel CAD

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Section: Analyses Of Correlations Of the Fmd And Imt With Inflammator...mentioning

confidence: 99%

Correlations of High-frequency Ultrasound Evaluation of Brachial Artery Endothelial Dilatation and Carotid Atherosclerosis with Glucose and Lipid Metabolism, Inflammatory Cytokines, Severity of Coronary Artery Disease and Vascular Endothelial Function in Elderly Patients

Cheng¹,

Sun²,

Yin³

et al. 2022

Cell Mol Biol (Noisy-le-grand)

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“…In fact, research in this area focuses on improving the spatial resolution, the temporal criterion and the chosen sensitivity of the methods of simulation and estimation [3], [4]. We put forward in this case two methods: the estimation and simulation methods [5]. In particular, estimators exploit the knowledge obtained a priori by using a measure of motion (propulsion of blood / cardiac flow).…”

Section: Introductionmentioning

confidence: 99%

Moving Towards a 5d Cardiac Model

Sakly¹,

Mahmoudi²,

Akil³

et al. 2019

J Flow Vis Image Proc

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The medical diagnosis process requires several steps to identify the types of cardiac pathologies. The segmentation step is used to determine the measurements for cardiac abnormalities on the short axis of the 4D acquired in MRI, but this phase remains limited on the blood flow sequences. The MRI modality allow to the experts to quantify the stenosis and the regurgitation of aortic blood flow. The parameters extracted from the flow sequences, after segmentation, make it possible to identify the valvular pathologies, but they are not sufficient to complete the medical prognosis as well as the lack of precision of these measurements. In this paper, we propose to make a coupling between the 4D cardiac cuts with their study of blood flow through the technique of registration and reconstruction. The interest of the purpose of the blood flow as fifth dimension is to improve the accuracy of the cardiac parameters and the extracting of measurements for valvulopathies in the process of assistance to the decision for the experts An example was introduced in this context through the development of cloud services for patient-specific simulations of blood flows through aortic valves as well as an OsiriX software for 5D visualization that combines a 4D sequence and the functional flow dimension. In this framework, we proposed a processing chain to lead towards a 5D solution. Another problem is raised is the choice of the appropriate architecture to solve the problem of hybrid parallelization for the processing of these cardiac images. To test the constraints of time of the concept of 5D, we need a GPU graphics processor acquired in MRI, as well as a CPU processor to perform the complexity of calculation and the operations applied to the algorithms of image processing.

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Feasibility Verification of Blood Viscosity Estimation by Two-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Analysis

Kadowaki

Kishimoto

Tokunaga

et al. 2021

Journal of Engineering and Science in Medical Diagnostics and Therapy

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Although blood viscosity has attracted much attention for its effect on hemodynamic parameters related to atherosclerosis, quantitative method for evaluating blood viscosity in vivo is not currently established. The purpose of this study was to verify the feasibility of blood viscosity estimation by a two-dimensional ultrasonic-measurement-integrated (2D-UMI) analysis system that computes an intravascular blood flow field by feeding back an ultrasonic measurement data to a numerical simulation. A method to estimate blood viscosity was proposed by reproducing the flow field of an analysis object in the feedback domain of ultrasonic Doppler velocity in a 2D-UMI blood flow analysis system, and evaluating the variation of the Doppler velocity caused by the analysis viscosity in the non-feedback domain at the downstream side. In a numerical experiment, a viscosity estimation was performed for numerical solutions of sinusoidal oscillating flows analyzed as a blood flow model in a human common carotid artery at four different types of blood viscosities. The estimation viscosities were made to correspond to those of all analysis objects by giving proper conditions on the feedback gain and feedback domain to optimize the accuracy of the 2D-UMI blood flow analysis. In conclusion, the feasibility of blood viscosity estimation by 2D-UMI analysis was established. Simultaneous measurement of the in vivo blood viscosity and flow field can be easily performed in many clinical cases by its widespread use at clinical sites, thereby clarifying the relationship between hemodynamics and vascular pathology for various blood flow fields.

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Study of Estimation Method for Unsteady Inflow Velocity in Two-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Simulation

Cited by 3 publications

References 17 publications

Correlations of High-frequency Ultrasound Evaluation of Brachial Artery Endothelial Dilatation and Carotid Atherosclerosis with Glucose and Lipid Metabolism, Inflammatory Cytokines, Severity of Coronary Artery Disease and Vascular Endothelial Function in Elderly Patients

Correlations of High-frequency Ultrasound Evaluation of Brachial Artery Endothelial Dilatation and Carotid Atherosclerosis with Glucose and Lipid Metabolism, Inflammatory Cytokines, Severity of Coronary Artery Disease and Vascular Endothelial Function in Elderly Patients

Moving Towards a 5d Cardiac Model

Feasibility Verification of Blood Viscosity Estimation by Two-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Analysis

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