Study of factors influencing central corneal thickness among patients attending ophthalmology outpatient department at a tertiary care center in North Kerala

Varghese, Vivek Oommen; Vadakkemadam, Latha N; Jacob, Shamin; Praveena, KK; Raj, Ratheesh; Kizhakkepatt, Jipina

doi:10.4103/kjo.kjo_9_17

Kerala J Ophthalmol

2016

DOI: 10.4103/kjo.kjo_9_17

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Study of factors influencing central corneal thickness among patients attending ophthalmology outpatient department at a tertiary care center in North Kerala

Vivek Oommen Varghese¹,

Latha N Vadakkemadam²,

Shamin Jacob³

et al.

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Study of corneal endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty

Kamhawy,

Salem,

El Zankalony

et al. 2023

Journal of the Egyptian Ophthalmological Society

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Background To study the endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty (DMEK) using specular microscopy to provide data about the endothelial cell density (ECD), endothelial cell loss (ECL) percentage, and changes in endothelial cell shape (hexagonality) and size [coefficient of variation (CV)] and to study the factors causing these changes in endothelial cell layer after DMEK. Patients and methods This study included 20 patients investigated by specular microscopy 3 months after DMEK. We discuss the postoperative ECD, factors that affect the ECD, factors that affect hexagonality and CV, visual outcome, and advantages of DMEK. The study was approved by the ethics committee of Ain Shams University. Results This study showed that the mean ECD postoperative was 1664.80 cells/mm2, with mean ECL of 34.67%. This cell loss increased in cases of difficult graft unfolding. Donor age and preservation time had no effect on postoperative ECD. A percentage decrease in hexagonal cells and a percentage increase in CV were noticed in cases that received grafts from donors with history of diabetes mellitus. Postoperative ECD and hexagonal cell percentage had no correlation with central corneal thickness in this study. Conclusion DMEK results in significant improvement of postoperatively visual acuity (VA). Advantages of DMEK like no corneal sutures, short recovery time, less cylindrical aberration, decreased incidence of graft rejection, and good visual outcome make it the best choice to treat eyes with corneal endothelial dysfunction.

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Study of corneal endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty

Kamhawy,

Salem,

El Zankalony

et al. 2023

Journal of the Egyptian Ophthalmological Society

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Effect of Age Under 20-60 years on Central Corneal Thickness

Hussain

Tariq²,

Rehman³

et al. 2022

PBMJ

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The measurement of central corneal thickness is an important measure for the diagnosis of corneal pathologies. 510–520 microns is the standard central corneal thickness. Optical or ultrasound techniques are used for the measurement of thickness CCT. Objectives: To evaluate the effect of age on central corneal thickness in normal population visiting The University of Lahore Teaching Hospital, Raiwind road Lahore. Methods: Descriptive study design was used. Data was obtained from The University of Lahore Teaching Hospital, Raiwind road Lahore. The sample size of patients was 147 with ages ranging from 20 to 60 years. All genders were included in the data collection. Data were collected through convenient sampling technique by using researcher administrative performa and study was finalized in three months after the approval of synopsis. Data entry and analysis were done using computer software SPSS version 25.0. CCT was measured by non-contact Pachymeter (Canon TX-20P) and values were represented in the form of frequency tables and bar charts. Results: CCT drops over time, resulting in thinner corneas in older people. The dependence of CCT on age is greater in men. Mean CCT in male individuals were 538.66 µm and in females mean CCT was 540.37µm. In this study mean central corneal thickness values of right and left eyes were also compared. In males right mean CCT value was 537.94 µm and left mean CCT was 539.39µm. In females the mean CCT value of right was540.28µm and left mean CCT value was 540.47µm. Conclusions: The Central Corneal Thickness decreases with age. Men have thinner corneas than females in every age group.

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Study of factors influencing central corneal thickness among patients attending ophthalmology outpatient department at a tertiary care center in North Kerala

Cited by 2 publications

References 2 publications

Study of corneal endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty

Study of corneal endothelial cell layer 3 months after Descemet membrane endothelial keratoplasty

Effect of Age Under 20-60 years on Central Corneal Thickness

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