Study of glass transition in functionalized poly(itaconate)s by differential scanning calorimetry, Raman spectroscopy and thermogravimetric analysis

Some PluronicF68 (F68) triblock copolymer properties demonstrate surprising applications in selective drug administration, such as the transportation of hydrophobic anti-inflammatories through epithelial barriers. Nuclear magnetic resonance ( 1 H-NMR) spectroscopy was carried out for micelle precursor dispersions and F68 films modified with a synthetic imogolite (IMO) biocompatible hydrogel. Theoretical calculations and morphological assessment for the process of morphogenesis of dendritic crystallization were performed by molecular docking and atomic force microscopy (AFM) of the Sudan III-IMO-F68 composite, which was more hydrophobic than Sudan III-F68 and carried out the prolonged release of the Sudan III “drug” captured by a water–octanol interface determined by standard absorbance. Surface fusions were measured and compared to the unmodified matrix. However, despite the superior properties of the composite, the critical micelle concentration (CMC) was practically unmodified because solitary IMO strands attached to Sudan III formed Sudan III-IMO. These strands unraveled in a stable manner by expanding like a “spiderweb” in hydrophilic interfaces according to NMR analysis of the hydrogen one H 1 polarization of Sudan III and F68 methyl, whose correlation relates hydrophobicity of Sudan III-IMO-F68 with dendrite properties from F68 concentrations. CMC and surface fusions equivalent to F68 surface properties, calculated by differential scanning calorimetry and dynamic Raman spectroscopy, were determined by AFM and high-resolution ellipsometry. Our results show highly specialized pharmacological applications since micelle surfaces expand, triggering maximum deliveries of “Drugs” from its interior to the physiological environment. The implanted sensor prototype determined equilibria reached Sudan III according to temperature (32–50 °C) and time it took to cross the membrane model 1-octanol (48 h). The findings suggest that the targested design of a F68-IMO-“Drug” would function as a microdevice for the prolonged release of hydrophobic drugs. In addition, the said microdevice could regenerate the damaged tissue in the central nervous system or other organs of the body. This is due to the fact that it could perform both tasks simultaneously, given the properties and characteristics acquired by the compatible material depending on the temperature of the physiological environment.

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“…The melting temperature was then determined in the 25–100 °C range at a heating rate of 20 °C/min in a nitrogen atmosphere. 51 , 52 …”

Section: Experimental Methodsmentioning

confidence: 99%

“… 53 , 54 To guarantee the sample/sample holder thermal equilibrium, the temperature was stabilized for 1 min before running each spectrum. 40 , 51 , 55 …”

Section: Experimental Methodsmentioning

confidence: 99%

Morphological and Semi-empirical Study of the Pluronic F68/Imogolite/Sudan III Intersurfaces Composite for the Controlled Temperature Release of Hydrophobic Drugs

2020

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“…The temperature program started with 1 min holding at 20 °C, followed by increased temperature at 10 °C min −1 to 100 °C, and with 1 min holding at 100 °C. As a standard criterion, the peak point of the melting curve was taken as T m , and the midpoint of the glass transition curve was referred as T g (Samith and Ramos‐Moore, ). The binder that had the highest hardness, adhesion, and T g was selected to form the BMD mixture for binding performance evaluation.…”

Section: Methodsmentioning

confidence: 99%

A Soybean Oil‐Based Adhesive and Its Application for Birdseed Binding

Tao

Slagle

Jarboe

et al. 2018

J Americ Oil Chem Soc

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Current birdseed binders are mainly based on animal protein and fat. However, exporting the seed cakes containing animal products to European countries can be difficult due to their import policies. A plant oil-based adhesive may be capable of binding loose seeds together, enabling it to be used as an alternative to the animal protein-based and fat-based binders used currently and making the exportation possible. A soybean oil-based adhesive was, therefore, synthesized and tested for birdseed binding in this study. The effects of the quantity of saturated fatty acylglycerols (i.e., fully hydrogenated soybean oil, FHSO) introduced into epoxidized soybean oil (ESO) and a phosphoric acid (H 3 PO 4 ) cross-linker on product characteristics were investigated. Increased quantity of FHSO improved the glass transition point (T g ), hardness, and adhesion while further increasing the quantity led to various degrees of phase separation of the product. Increased quantity of H 3 PO 4 also improved hardness and adhesion of the binder. A binder-MDAG (a mixture of mono and diacylglycerols at about a 1:1 ratio as a hardening agent) mixture (BMD) having an average hardness and adhesion of 4024 and 1197 g, respectively, was selected for seed binding. Seed cakes bound with 15 wt.% BMD were about twice as hard as gelatin-bound ones. Storage of the BMD itself in open air led to increased hardness, adhesion, and melting point, and storage of the seed cakes bound by BMD in open air led to increased hardness and high temperature tolerance. Seed cakes bound with BMD also presented much better water resistance.Keywords Epoxidized soybean oil Á Fully hydrogenated soybean oil Á Phosphoric acid-based and soybean oil-based seed binder J Am Oil Chem Soc (2019) 96: 179-187.

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“…The frequency shift is due to the change of the relative amount of glassy and crystalline components of the material with the temperature [1]. Besides, at Tg, Raman modes are also affected by the discontinuity in the thermal expansion and other physical properties, which are directly correlated to intermolecular interactions.…”

Section: T(°c)mentioning

confidence: 99%

“…In amorphous materials this is the primary transition. Tg is a very important parameter to be considered in order to objectively evaluate the performance of a material because it primarily affects the chemical and physical properties such as heat capacity, linear coefficient of thermal expansion and elasticity [1]. Polymers have several different phases (glassy, LC, crystalline and isotropic).…”

Section: Introductionmentioning

confidence: 99%

Detection of the Glass Transition of Polymers Used in Art and Art-Conservation Using Raman Spectroscopy

Osticioli

Mencaglia

Ciofini

et al. 2016

18th Italian National Conference on Photonic Technologies (Fotonica 2016)

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In this work Raman spectroscopy was employed for the detection of the glass transition temperatures (Tg) of some thermoplastic polymers and natural terpenoid resins. In particular, our attention was focused on evaluating the Tg of polystyrene and colophony. The measurements returned Tg values in accordance with those reported in the literature obtained using the DSC technique, thus confirming the reliability of the approach proposed herein. Further studies will be focused on the evaluation of Tg temperature changes depending on materials treatments and ageing.

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Study of glass transition in functionalized poly(itaconate)s by differential scanning calorimetry, Raman spectroscopy and thermogravimetric analysis

Cited by 14 publications

References 27 publications

Morphological and Semi-empirical Study of the Pluronic F68/Imogolite/Sudan III Intersurfaces Composite for the Controlled Temperature Release of Hydrophobic Drugs

Morphological and Semi-empirical Study of the Pluronic F68/Imogolite/Sudan III Intersurfaces Composite for the Controlled Temperature Release of Hydrophobic Drugs

A Soybean Oil‐Based Adhesive and Its Application for Birdseed Binding

Detection of the Glass Transition of Polymers Used in Art and Art-Conservation Using Raman Spectroscopy

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