“…For applications development, recent progress of laser systems combining high intensity and high repetition rate have attracted considerable interest for the production of solid target based secondary sources where high mean brightness is required. In high field science, this includes bright x-ray sources (Chen et al, 2004;Schnürer et al, 2000;Teubner et al, 2003;Thaury et al, 2007), high energy particle acceleration (Fritzler et al, 2003;Steinke et al, 2010;Zeil et al, 2010) and nuclear activation (Grillon et al, 2002;Magill et al, 2003). To illustrate this interest for high peak intensities, recently published scaling laws for laser based proton acceleration on thin film solid targets (Fuchs et al, 2006) have shown that an important increase of the on target laser intensity is necessary to reach the expected energy required for biomedical application in the proton therapy field (60 -250 MeV).…”