Study of insulin status in metabolic syndrome in correlation with presence of other risk factors

Abstract

Recent studies in India shows that about one third of urban population in major cities has metabolic syndrome. 3 The majority of persons with metabolic syndrome have insulin resistance. Insulin resistance and/or associated hyperinsulinemia are believed to be the direct cause of other metabolic syndrome risk factors. 4 Insulin resistance is usually caused by a defect in insulin action within target organs and tissues that result in compensatory hyperinsulinemia. 5 It has been proved that insulin resistance and hyperinsulinemia are closely linked. 6 Although hyperinsulinemia may compensate for insulin resistance to some biological actions of insulin,