Study of Lipid Profile, Estradiol for Evaluation of Cardiovascular Risk in Pre- and Post-Menopausal Women

Warjukar, Prajakta; Jha, Rakesh Kumar; Kute, Prakash

doi:10.31782/ijcrr.2020.12179

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…20,21 The previous literature has evidenced that estrogen level is reduced among menopausal women and has a close relationship with the lipid profile. 15,18,22 Therefore, it could be possible that we have observed a difference in lipid components, more specifically higher levels of TG and TC among postmenopausal women, who may have a lower estrogen level. Elevated TG along with FSH in a postmenopausal state is associated with an increase in atherogenic lipid parameters and increased insulin resistance.…”

Section: Discussionmentioning

confidence: 94%

“…Although the link between menstrual status and estrogen level has not been studied in the present study, the previous studies have shown link between menstrual status and estrogen level. 17 Indeed, a previous study has shown the protective role of estrogen in the cardiac system of premenopausal women compared to the postmenopausal 18 or the comparable age of male, 28 which may be linked to the association of estrogen to lipid profile, 18 that is, further related to CVD risk. 22 The strength of our study lies in the fact that it supported previous findings that menstrual status alters the lipid profile in postmenopausal women.…”

Section: Discussionmentioning

confidence: 98%

“…13,14 Postmenopausal women have been associated with higher levels of HDL-C, LDL-C, and TC. 15,16 As relationship between menstrual status and increased or decreased level of estrogen in corresponding state has been established by the previous literatures, 17,18 our research group wanted to examine the level of impact menstrual status had on the lipid profile of women.…”

Section: Introductionmentioning

confidence: 99%

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Effect of menstrual status on lipid profile: A cross-sectional study in a tertiary care hospital in Nepal

Adhikaree,

Shrestha,

Bomjan

et al. 2023

Post Reprod Health

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Background: The ovarian follicular cell's degradation and subsequent decrease in the synthesis of estrogen results in the decreased cardiovascular protection. As a result, the incidence of cardiovascular disease (CVD) increases in postmenopausal women and is characterized by change in lipid profile. This study sought to ascertain the extent of the impact that menstrual status might have on lipid profiles among premenopausal and postmenopausal women. Methods: A cross-sectional study was conducted with 260 premenopausal and postmenopausal women (1: 1) and serum lipid component concentrations (high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TGs), and total cholesterol (TC)) were measured. A comparison between two groups was made between premenopausal and postmenopausal women, and regression was carried out to estimate the effect of menstrual status on lipid components. Results: Compared with premenopausal women, the concentrations of the lipid components (HDL-C, LDL-C, TG, and TC) were found to be significantly higher in postmenopausal women. Using the linear regression, menstruation status was able to predict 11.7%–13.3% of the lipid components (TG and TC) when age and weight were adjusted. Conclusion: The difference in lipid components between premenopausal women and postmenopausal women exists, with menstrual status explaining 11.7%–13.3% variance for the observed lipid level. The factors influencing the lipid profile beside the menstrual status should also be explored. External intervention such as estrogen replacement therapy is also recommended in case of deviation of lipid profile from the suggested normal clinical range.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Effect of menstrual status on lipid profile: A cross-sectional study in a tertiary care hospital in Nepal

Adhikaree,

Shrestha,

Bomjan

et al. 2023

Post Reprod Health

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“…So, 6 weeks of proper Pilates intervention were programmed [5]. [17][18][19][20]. Few more related were reviewed [21][22][23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

Impact of 6 Weeks Pilates Training on Menopause Specific Symptoms and Quality of Life in Menopausal Women: A Case Report

Bais

Mishra

Darda

et al. 2021

JPRI

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Introduction: The concept of menopause is a complete cessation of ovarian function. Most common symptom of menopause include muscle and joint ache, poor memory, lower back pain and trouble sleeping. The vasomotor and emotional domains reported less often compared with the physical and psychological domains. Such adverse changes in physical and mental health may have a negative impact on Quality of Life (QOL). Pilates is a mind body exercise focusing on muscle strength, core stability, endurance, muscle control, posture, and respiration which seems to improve both the physical and psychological components in women during menopause. The given study helps to provide the effect of 6 weeks Pilates training protocol on menopausal women’s presenting complaints as well as on her QOL. Complaints and clinical finding: Patient’s main concern were low back ache without any cause night sweats, fatigue, disturbed sleep wake cycle which lead to difficulties in performing activities of daily living which hampered the QOL of the patient. Physical findings revealed decrement in lower back and lower limb muscle strength along with some tightness. Scales helped to reveal that patient is having fatigue and tiredness and mat-exercise treatment protocol were formed. Therapeutic Intervention: 6 weeks Pilates training. Conclusion: As there are minimal to no evidence present in reference to this study, it helps us to provide new and proper treatment protocol and it is helpful to know the effect of the same. It showed significant improvement in the muscular strength as well as reduction in stress level and helped in enhancing the QOL of the patient.

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Beyond reproduction: unraveling the impact of sex hormones on cardiometabolic health

Xega,

Liu

2024

Medical Review

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This review thoroughly explores the multifaceted roles of sexual hormones, emphasizing their impact beyond reproductive functions and underscoring their significant influence on cardiometabolic regulation. It analyzes the broader physiological implications of estrogen, testosterone, and progesterone, highlighting their effects on metabolic syndrome, lipid metabolism, glucose homeostasis, and cardiovascular health. Drawing from diverse molecular, clinical, and therapeutic studies, the paper delves into the intricate interplay between these hormones and cardiometabolic processes. By presenting a comprehensive analysis that goes beyond traditional perspectives, and recognizing sexual hormones as more than reproductive agents, the review sheds light on their broader significance in health and disease management, advocating for holistic and personalized medical approaches.

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Study of Lipid Profile, Estradiol for Evaluation of Cardiovascular Risk in Pre- and Post-Menopausal Women

Cited by 4 publications

References 10 publications

Effect of menstrual status on lipid profile: A cross-sectional study in a tertiary care hospital in Nepal

Effect of menstrual status on lipid profile: A cross-sectional study in a tertiary care hospital in Nepal

Impact of 6 Weeks Pilates Training on Menopause Specific Symptoms and Quality of Life in Menopausal Women: A Case Report

Beyond reproduction: unraveling the impact of sex hormones on cardiometabolic health

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