Study of Lipid Profile in Eclampsia

Abstract

BACKGROUND Eclampsia occurs in about 1.56% of pregnancies in our country and is an important cause of foetal and maternal morbidity and mortality. Altered lipid synthesis leading to decrease in PGI2:TxA2 ratio is also supposed to be an important way of pathogenesis in pregnancy-induced hypertension leading to eclampsia. The aim of this study was to determine and compare the serum lipid levels among women with eclampsia and women having normal pregnancy without hypertension. MATERIALS AND METHODS This is a descriptive comparative study where lipid profile of 100 normal pregnant women was compared with 100 eclamptic women. RESULTS Serum cholesterol, LDL & VLDL showed a steady rise with an increase in systolic and diastolic blood pressure. The range of serum HDL showed a steady fall with an increase in systolic & diastolic blood pressure. CONCLUSION There was an increase in the level of serum cholesterol, serum triglycerides, HDL, LDL and VLDL in the eclamptic subjects but not in the control group of normal pregnant women, thus eclamptic women had deranged lipid profile due to abnormal lipid metabolism.

Examination of the Lipid Profile in Pregnant Obese Women, Considering the Allele Status of the Genes of Angiotensin-Converting Enzyme (Ace I / D) and Plasminogen-1 (Pa-1 4g / 5g) Activator-Inhibitor

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