Study of Lipoprotein (A) Levels as a Risk Factor in Patients With Essential Hypertension in a Tertiary Care Hospital

Abstract

BACKGROUNDLipoprotein (a) has been identified as an important, independent, causal risk factor for various cardiovascular diseases, but its association with hypertension has shown differing results. The studies regarding this association are limited. AIMS AND OBJECTIVESIn the present study, the levels of Lp (a) and other lipid parameters like Serum Total Cholesterol, Serum LDL Cholesterol, Serum HDL Cholesterol, serum triglycerides have been studied in hypertensive and non-hypertensive patients to investigate any significant relationship between the same. MATERIALS AND METHODS30 essential hypertensive patients were selected and were compared with 30 controls matched in terms of age and sex. Lipid profile including Total cholesterol, LDL-Cholesterol, HDL-Cholesterol, Triglycerides and Lp (a) were studied in both groups. RESULTSHypertensive patients were observed to have higher levels of Serum Total Cholesterol, Serum Triglycerides, Serum LDL cholesterol, but it was not found to be significant. But lipoprotein (a) was found to be significantly higher (p<0.01) in cases than in controls.