Study of lymphatic mapping and sentinel node identification in early stage cervical cancer

Sentinel node detection with 99mTc phytate alone is satisfactory for cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy

“…In the subgroups of patients with stage Ia-Ib1 disease and smaller tumor size (B3 cm in diameter), SLN detection rate increased to 95%. The rates are comparable with findings from studies on cervical cancer that used both radioisotope and blue dye injection technique (Table 5) [8][9][10][11][12][13][14][15][16][17]. One of the reasons we achieved comparable results with scintigraphy only is the availability of 99m Tc phytate, which we used as the radioisotope tracer.…”

“…SLNs are often detected by both preoperative radioisotope injection using 99m Tc and intraoperative blue dye injection [8][9][10][11][12][13][14][15][16][17]. However, the SLN detection rate is low with blue dye alone, and intraoperative injection into the uterine cervix is bothersome.…”

Risk factors for lower-limb lymphedema after surgery for cervical cancer

“…Indeed, it has been reported that SFN metastases are accompanied with multiple lymph node metastases, and only 8% of patients with any positive regional nodes have SFN metastases [18]. Moreover, SFNs are seldom identified as sentinel lymph nodes in cervical cancer [22][23][24][25][26]. It would be worthwhile to conduct a randomized control study to evaluate whether SFN dissection is essential to improve disease-free survival and overall survival and to design a strategy to assess the necessity of SFN dissection for individual patients.…”

Up-to-date management of lymph node metastasis and the role of tailored lymphadenectomy in cervical cancer

“…The median or mean number of pelvic lymph nodes removed in lymphadenectomy varies among studies, at 13 to 56.4. [9][10][11][12][13][14][15][16][17][18] The reported numbers of lymph nodes removed in systematic lymphadenectomy in the pelvic and paraaortic areas are shown in Table 1.…”