The first results about the features of the fission fragments yields and spectrum of the energy of fission over 100 isotopes of uranium are presented. The role of neutrons shells with N = 82 or N = 126 and protons shells with Z = 50 in the realization of symmetric (or onehumped) and asymmetric (2-or 3-humped) shapes of the fission fragment yields was investigated. It was shown that studies of Kr isotope yields under fission of uranium isotopes give also valuable information on the role of the mentioned nuclear shells, too. The obtained results can be useful in similar studies of other actinide nuclei.