Study of Medical Management of Ectopic Pregnancies

Abstract

BACKGROUNDEctopic pregnancy is a significant cause of morbidity and mortality in the first trimester of pregnancy. Treatment with Methotrexate (MTX), an antimetabolite chemotherapeutic agent that binds to the enzyme dihydrofolate reductase, which is involved in the synthesis of purine nucleotides. This interferes with DNA synthesis and disrupts cell multiplications, achieves results comparable to surgery for treatment of appropriately selected ectopic pregnancies. Surgery is specifically indicated in ruptured ectopic and when MTX is contraindicated. Aim-To evaluate the medical management of Ectopic pregnancy in tertiary care hospital.