Study of Mimusops elengi bark in experimental gastric ulcers

Characterization of the molluscicidal activity of Bauhinia variegata and Mimusops elengi plant extracts against the fasciola vector lymnaea acuminata

“…Earlier, it has been reported that saponins are potent molluscicides 20,26,27,33 . Pharmacological and biological effects of saponin as antibacterial 7 , antihelmintic 13 , antigastric ulcer 23 and hypotensive 4 have been noted. Methanol extract of Mimusops elengi bark and seed shows significant antifungal activity 21 .…”

Antiulcer activity of ethanol leaf extract ofCassia fistula

“…In the present study, pre-treatment of pylorus-ligated rats with ranitidine (group II) and 750 mg/kg of ELE (group V) produced a comparable antiulcer activity, as evidenced by a reduction in the increase in gastric volume, pH, and free and total acidity ( Table 1). The methanol bark extract of Mimusops elengi L. (Sapotaceae) (Shah et al, 2003) and flower extract of Hemidesmus indicus R. Br. (Asclepiadaceae) (Anoop & Jegadeesan, 2003) were reported to reduce total acidity and volume of gastric acid secretion in gastric ulcer-induced rats, and this antiulcer activity was attributed to strengthening of the mucosal defense mechanism by these plant extracts.…”

“…Several plant extracts have been shown to increase hexosamine and hexose accompanied by a reduction in the concentration of sialic acid and fucose followed by an increase in the C:P ratio in pylorus-ligated or gastric ulcer-induced rats (Pillai & Santakumari, 1984;Anoop & Jegadeesan, 2003;Shah et al, 2003;Rao et al, 2004), and it is reported that these extracts exhibit antiulcer activity by protection of the mucosal barrier system leading to more production of mucus, resulting in less degree of ulceration. It is postulated that the higher is the mucus production, the higher will be the mucin content and the lower will be the free acidity (Anoop & Jegadeesan, 2003).…”

Assessment of the in vitro cytotoxicity and in vivo anti-tumor activity of the alcoholic stem bark extract/fractions of Mimusops elengi Linn.

“…Various parts of the plant have been reportedly used in traditional medicine. Leaves show antioxidant activity while the bark exhibits antimicrobial, anti-ulcer and anti-hyperglycemic activity (Jerline et al 2009), wound healing, anti-inflammatory, analgesic and antipyretic activity (Shah et al 2003). Fruit of this plant has antioxidant property (Boonyuen et al 2009) and antibacterial activity (Ali et al 2008).…”