Abstract:Currently, gene therapy is considered as a potentially universal approach to the treatment of a wide range of diseases, such as cancer, cardiovascular diseases, diabetes, inherited diseases, and many others. It is known that "naked" nucleic acid is not able to effectively overcome the extraand intracellular barriers to reach the target cell, since it is easily degraded. In this regard, it becomes necessary to create special delivery vehicles. We investigated the modular arginine-rich cysteine-flanked polyconde… Show more
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