Study of placental location and pregnancy outcome

Nair, Vidhu V.; Nair, Sobha S.; Radhamany, K

doi:10.18203/2320-1770.ijrcog20191187

Cited by 6 publications

(4 citation statements)

References 14 publications

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“…Our results coincide with those of other authors who have found that the use of mid-trimester ultrasound screening techniques can predict the risk of pe [37]. Some authors link placental laterality and the high risk of hypertension in pregnant women [35,36], which also coincides with our findings. The development of eclampsia can also be associated with adolescence, and age over 35 years -with hypertension [28].…”

Section: Discussionsupporting

confidence: 93%

The model of screening for preeclampsia in the second and third trimesters of gestation

et al. 2023

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Purpose: Preeclampsia (PE) is a specific syndrome of multiple organ insufficiency in case of pregnancy, which is included in the panel of major obstetric syndromes and is among the main causes of maternal morbidity and mortality in the whole world. Material and methods: We conducted a prospective cohort study of 91 pregnant women to evaluate the effectiveness of integrated use of maternal risk factors (2019 International Federation of Gynecology and Obstetrics recommendations), placenta location (ultrasound at 18-20 weeks of gestation), and serum cystatin C (at 18-36 weeks of gestation) in screening for pe in the second and third trimesters of gestation. Results: In the subgroup of pregnant women with cystatin C levels greater than 1.0 mg/L (27 women), PE developed in 26 women, which is 96.29% in percentage terms. When calculating GFR for cystatin C in a group with PE there was a significant violation of the renal filtration system -52.46±2.08 (95% CI, 48.39-56.54), while in healthy group the indicator is within normal limits -97.6±1.64 (95% CI, 94.38-100.82). In the analysis of the ratio of cystatin C levels more than 1.0 mg / l and the development of PE, a sensitivity of 98.46%, specificity of 100% and accuracy of 98.9%, p<0.001. Conclusions: The data show that the combined model of maternal factors, ultrasound of the placenta and serum cystatin C, is prognostically effective in pregnant women in the second and third trimesters of gestation and is a reliable marker for the development of pe.

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Section: Discussionsupporting

confidence: 93%

The model of screening for preeclampsia in the second and third trimesters of gestation

et al. 2023

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“…2022 Mar;11(3):803-807 Nair studied, 450 singleton pregnancies, frequency of central placenta was 377 (83.8%) and lateral placenta in 73 (16.2%). 12 Central placentation had an abnormal outcome in 182 (48.3%), lateral placentas with abnormal outcome were 44 (60.3%). Abnormal maternal outcomes like hypertensive disorders (33.3%), intra uterine growth restriction (10.2%), antepartum haemorrhage (25%), preterm birth (16.3%) were more in lateral placentation.…”

Section: Resultsmentioning

confidence: 99%

Study of correlation between fetomaternal outcome with placental location at a tertiary hospital

Sitimani

Sai

et al. 2022

Int J Reprod Contracept Obstet Gynecol

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Background: The site of implantation and location of placenta can affect the blood supply of placenta which is likely important determinant of placental blood flow and pregnancy outcome.Methods: In our study 240 pregnant women of 19-35 years, singleton ≥28 weeks underwent ultrasound examination for placental localization.Results: Majority of pregnant women were from 21-25 years age, multigravida and placental location in majority was lateral. Adverse events were PROM, preeclampsia/ eclampsia, IUGR, preterm birth was noted with lateral location of placenta.Conclusions: A significant association was noted between lateral placentation of placenta and adverse fetomaternal outcome. Ultrasound examination can be used as non-invasive predictor of adverse pregnancy and neonatal outcomes.

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“…In the study by Nair VV et al, central placental location was most common [18]. Abnormal outcomes such as gestational hypertension, preeclampsia, IUGR, antepartum haemorrhage, preterm delivery, NICU admission was significantly associated with lateral placental location.…”

Section: Original Research Articlementioning

confidence: 91%

Correlation between placental location and maternal fetal outcome

Dhingra¹,

K.³

et al. 2019

Obs Gyne Reivew J Obstet Gynecol

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Background: Placenta is the vital link between fetus and the uterine wall. Based on location, it can be classified as anterior, posterior, lateral, fundal and low lying. Placental location can be easily determined in the antenatal period using ultrasound. Materials and Methods: Design: Prospective observational study. Study period: One year from January 2018 to February 2019 in a tertiary hospital in Salem district of Tamilnadu. Study population: After informed consent, 200 women with singleton pregnancy of ≥28 weeks attending antenatal OPD were included in the study. Women were followed up with ultrasound at 28 weeks and 34 weeks to identify any maternal and fetal adverse effects such as gestational hypertension, preeclampsia, preterm birth and NICU admission. Results: The mean age of the study participants was 24.3 ± 43 years. Of the 200 women, 42% (n=84) of placenta were situated in fundus, 30% (n=60) were anterior, 18% (n=36) were lateral, 8% (n=16) were posterior and 2% (n=4) were low lying. Gestational hypertension was present in 22%, 13%, 12% in lateral, anterior and posterior placental location respectively. Preeclampsia was seen in 22% in lateral placental location. Preterm labour, PROM, low birth weight and NICU admission were common in posterior and lateral placental location.Conclusion:There was statistically significant association between low lying, posterior and lateral placental location and adverse maternal fetal outcomes. Hence ultrasound can be used as the safe, cost effective, non-invasive tool in predicting the adverse maternal and neonatal outcome.

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Study of placental location and pregnancy outcome

Cited by 6 publications

References 14 publications

The model of screening for preeclampsia in the second and third trimesters of gestation

The model of screening for preeclampsia in the second and third trimesters of gestation

Study of correlation between fetomaternal outcome with placental location at a tertiary hospital

Correlation between placental location and maternal fetal outcome

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