Study of prescribing pattern of antimicrobial agents in an IPD of a tertiary care hospital in Ahmednagar

Nl, Kapure; Bb, Nayak; Ar, Raul; An, V.; Vijayprasad, S; Kp, Vakade; Ar, Jadhav

doi:10.5958/j.2319-5886.3.1.022

Cited by 2 publications

(3 citation statements)

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“…Similar findings were observed in many studies 12,13,14 . Amongst cephalosporins, third generation is the most commonly prescribed one.…”

Section: Discussionsupporting

confidence: 92%

Untitled

2018

IJPSR

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Objective: Antimicrobials have become one of the most misused therapeutic agents resulting in resistance. Present study was carried out to evaluate the antimicrobial drug utilization pattern. Method: A retrospective, observational record based study was done in hospitalized patients from medicine and surgery department of tertiary care hospital of central India over a period of one year. Result: Among 385 patients, 53.25% were females and 26.75% were in 41 -50 years age group. Amongst 775 antimicrobials prescribed, 75% were injectables. Average number of antimicrobials per prescription was 2.01 ± 0.6. Use of antimicrobial monotherapy (39.74%) was common and 25.71% had more than two antimicrobials. About 33.16% drugs were prescribed by generic names and FDCs were prescribed in 37.14%. Culture and sensitivity tests were done in 35.6% cases. Cephalosporins (65.19%) were the most preferred antimicrobials followed by penicillins, aminoglycosides and antiamoebics. Ceftriaxone, amikacin and metronidazole were the most commonly prescribed antimicrobials. Prescribed daily dose (PDD) was greater than defined daily dose (DDD) for ceftriaxone, amikacin, amoxicillin, metronidazole and levofloxacin indicating their wide usage. Conclusion: Antimicrobials' prescribing in our hospital is empirical; there is a need for strict antibiotic prescription policy. Generic drug prescribing should be encouraged. Such type of studies should be carried out regularly to evaluate the changes in the pattern and its rationality.

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“…Similar findings were observed in many studies 12,13,14 . Amongst cephalosporins, third generation is the most commonly prescribed one.…”

Section: Discussionsupporting

confidence: 92%

Untitled

2018

IJPSR

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“…Cefuroxime was the most commonly used cephalosporin (33.33%), followed by cefotaxime (25.39%), ceftriaxone (6.32%), and Cefoperazone. 16 Khan et al in their study β-lactams were mostly prescribed of which amoxicillin with clavulanic acid is the most commonly prescribed followed by ceftriaxone, levofloxacin, nitroimidazoles, aminoglycosides and the macrolides. 17 These findings are inconsistent with our study in which ceftriaxone was the most commonly used drug.…”

Section: Discussionmentioning

confidence: 99%

“…For the best antimicrobial medication, a multidisciplinary strategy can be used in the ICU and IPD setting, involving specialists in intensive care, infectious disease control, pharmacy, and microbiology. 16…”

Section: Discussionmentioning

confidence: 99%

Drug utilization study in acute febrile illnesses in a tertiary care hospital of central India

Quazi,

Siddiqui,

Shende

et al. 2023

PJMS

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Acute febrile illness (AFI) can be caused by various aetiologies. Different antimicrobials are available to be used depending on the cause. Also, there are interpersonal variations in the prescription of these antimicrobials. Antibiotic stewardship programs frequently employ antibiotic policies to reduce the needless use of drugs and improve management. As a result, the purpose of this study is to examine current patterns in the use of antibiotics in patients with acute febrile illness.It is an observational study based on records that were conducted at a tertiary care hospital. 300 patient case files with acute febrile illnesses were admitted to the Department of Medicine after analysing numerous etiologies for antibiotic usage. Antibiotics for different aetiologies of febrile sickness were noted in a case record form. Data collected were analysed for proportion to find the prescription pattern of antimicrobials.Respiratory tract infections, especially upper respiratory tract infections (URTI) (26.6%) are frequent clinical diseases for which antibiotics were administered followed by acute gastroenteritis (16%), urinary tract infection (UTI) (12.3%) and lower respiratory tract infection (LRTI) (9.6%), dengue fever (9%) & viral fever (8.3%). Ceftriaxone (20%) was one of the most frequently prescribed antibiotics and Piperacillin+ Tazobactum (16.25%) was followed by Amoxycillin + clavulanic acid (10.5%), Clarithromycin (8.5%), Cefuroxime (7.25%). According to our analysis, respiratory tract infections and gastrointestinal infections were the two conditions for which antibiotics were most frequently administered. Third-generation cephalosporins, particularly ceftriaxone and cefixime, were the most frequently used antibiotics.

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Study of prescribing pattern of antimicrobial agents in an IPD of a tertiary care hospital in Ahmednagar

Cited by 2 publications

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Drug utilization study in acute febrile illnesses in a tertiary care hospital of central India

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