2020
DOI: 10.1007/s12288-020-01291-y
|View full text |Cite
|
Sign up to set email alerts
|

Study of Prothrombotic Changes in Metabolic Syndrome

Abstract: The metabolic syndrome is a complex disorder of various metabolic risk factors in a single individual having central obesity and commonly associated with diabetes and cardiovascular diseases. The aim of our study was to study the relationship between coagulation abnormalities and metabolic syndrome. We performed a prospective cross-sectional study in a tertiary care hospital. A total of fifty cases of metabolic syndrome and fifty age & sex matched controls were selected. These two groups were investigated for … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
6
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 7 publications
(6 citation statements)
references
References 14 publications
0
6
0
Order By: Relevance
“…Metabolic syndrome (MetS) is a series of metabolic disorders of proteins, fats, carbohydrates and other natural substances 1 . It has a high prevalence worldwide and the morbidity is still increasing 2 , 3 .…”
Section: Introductionmentioning
confidence: 99%
“…Metabolic syndrome (MetS) is a series of metabolic disorders of proteins, fats, carbohydrates and other natural substances 1 . It has a high prevalence worldwide and the morbidity is still increasing 2 , 3 .…”
Section: Introductionmentioning
confidence: 99%
“…D-dimer is a specific product of degradation of cross-linked fibrin, which indirectly reflects the coagulation disorder. Accumulating evidence suggests that the hemostatic balance is impaired in patients with metabolic syndrome, including hypertriglyceridemia, [26,27] which may be related to the increasing level of plasma protein factor XII (FXII), endothelial dysfunction, [28] and the activation of platelets and the coagulation pathway by increased concentrations of very-low-density lipoprotein. [29] In recent years, the diagnostic value of PCT has attracted increasing attention in various diseases, and the present study found that it was closely related to the severity of HTG-AP (Spearman’s correlation, r = 0.642).…”
Section: Discussionmentioning
confidence: 99%
“…Obesity is a recognized risk factor for thrombosis. Obesity makes the body in a high coagulant state affect the number of platelets and coagulation factor activity and damage the primary and secondary hemostasis ability [15][16][17]. If combined with prolonged APTT, the risk of bleeding increased, which could increase the risk of mortality.…”
Section: Discussionmentioning
confidence: 99%