Study of receptor mediated selective anion transmembrane transport using parallel artificial membrane permeability assay

Abstract

The separation performance of inorganic anions ReO4(-), Br(-), SO4(2-), and NO3(-) using porphyrin-alkaloid quaternary salt transporters is examined using parallel artificial membrane permeability assay. Active and selective transport of perrhenate is achieved by porphyrin-brucine conjugates. Herein, chlorides are used as antiporters and complete removal of perrhenates from a source solution is stimulated due to electrostatic effects.

Design, Synthesis, Selective Recognition Properties and Targeted Drug Delivery Application

“…However, in the presence of sulfate and nitrate no such effect was observed. 95 It seems that different polarity and structure of porphyrinalkaloid conjugates (meta-and para-) ( Figure 18) with perrhenate and sulfate are playing an important role. 96 Porphyrin-sulfate complexes are more lipophilic and accordingly they can reach and remain in a lipophilic membrane, while more polar complexes of porphyrin with perrhenate are not able to pass into the membrane.…”