Study of Single Dose Carboprost in Terminating Pregnancy

Abstract

Medical termination of pregnancy. It also called induced abortion. It is the medical way of getting rid of unwanted pregnancy. Efficacy of the methods in achieving complete abortion is needed. The aim of the study is to evaluate induction abortion interval when intracervical prostaglandin-E2 gel was followed by carboprost IM injections. MATERIALS AND METHODS This was a prospective study for a period of 2 years. 50 cases were randomly selected from the patients attending the Gynaecology Outpatient Department seeking termination of pregnancy between 10-14 weeks of gestation. Patients are divided into 3 groups, Group-I: (25) intracervical application of 500 μg PGE2 gel, Group-II: Study group (25) 500 μg PGE2 gel was instilled intracervically. After 12 hours, carboprost injections were given intramuscularly at 3 rd hourly intervals. RESULTS Results were analysed in both the groups according to age, parity, reason for seeking abortion, preinduction cervical status, cervical dilatation after 12 hours in group I and in group II induction abortion interval, incidence of incomplete abortion and incidence of side effects. CONCLUSION Carboprost intramuscular injections 3 rd hourly found to be an effective and safe method of terminating pregnancy with induction abortion interval 19.8 hours in primi and 19.3 hours in multi with a success rate of 100%.