Study of soft tissue sarcomas over a period of 3 years

Jenna, Prabhakar; Sushma, Jain; Kartheek, B. V. S.; Lakshmi, A. Bhagya; Vaibhav, Chapara

doi:10.18203/2320-6012.ijrms20172469

Cited by 3 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sarcomas of soft tissues and bone are more common cancers in pediatric patients than in adults [Ramaswamy et al, 2016]. About 44% and 27% of soft tissue sarcomas (STS) occur in the lower and upper extremities of the body, respectively [Prabhakar et al, 2017]. Due to the higher incidence of late‐stage disease, aggressive and effective adjuvant treatment modality is needed for improved treatment outcomes.…”

Section: Introductionmentioning

confidence: 99%

Design of Site‐Specific Microwave Phased Array Hyperthermia Applicators Using 434 MHz Reduced Cavity‐Backed Patch Antenna

Baskaran

Arunachalam

2020

Bioelectromagnetics

View full text Add to dashboard Cite

Cancers of the neck, breast, and lower extremities are common malignancies diagnosed in India with a higher incidence of advanced-stage disease. Phased array (PA) applicators reported for hyperthermia treatment (HT) of the breast have small focal region and high cross-coupling, and those reported for lower extremities provide regional heating and limited steering. In this study, we present the numerical design of site-specific PA applicators for HT of large solid tumors in the neck, breast, and lower extremities using a miniaturized 434 MHz cavity-backed water-loaded patch antenna. The fabricated antenna has 38 × 36 mm 2 aperture, more than 90% power coupling, 25 MHz bandwidth, and good agreement between simulated and measured specific absorption rate (SAR) in phantom. The site-specific applicators demonstrated less power reflection (<−17.9 dB) and crosscoupling (<−26.8 dB) for 5 mm interring spacing. SAR indicators for 64 cc tumor at varying locations in simplified layered three-dimensional (3D) tissue models of the neck, breast, and leg showed average power absorption ratio (aPA ratio) ≥ 3.16, target to hotspot quotient (THQ) ≥ 0.57, 25% iso-SAR coverage (TC 25) ≥ 81%, and 50% iso-SAR coverage (TC 50) ≥51.8%. Simulation results of site-specific applicators for 3D inhomogeneous patient models showed aPA ratio ≥ 5.98, THQ ≥ 0.9, TC 50 ≥ 86%, and 100% TC 25 for all sites. It is concluded that the 434 MHz miniaturized cavity-backed patch antenna can be used to develop high-density PA applicators with 12-24 antennas for HT of large solid tumors (≥4 cm) in the neck, breast, and lower extremities with 3D steering ability and less cross-coupling (

show abstract

Section: Introductionmentioning

confidence: 99%

Design of Site‐Specific Microwave Phased Array Hyperthermia Applicators Using 434 MHz Reduced Cavity‐Backed Patch Antenna

Baskaran

Arunachalam

2020

Bioelectromagnetics

View full text Add to dashboard Cite

show abstract

Middle East observational study in metastatic soft tissue sarcoma: an epidemiological study on the treatment patterns (MOON)

Memon

Karaca

Aboelhassan

et al. 2018

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

show abstract

Clinico-pathological study of soft tissue tumors

Begum¹,

K²,

K³

et al. 2020

IJPO

View full text Add to dashboard Cite

Soft tissue tumors (STT) are a diverse group of tumors. The prognosis of soft tissue tumors is unpredictable and aggressive if not diagnosed early. A vast majority of STT are benign, having a very high cure rate following surgical excision. Benign tumors vary widely in appearance and behavior. The sub-classification of these benign tumors is essential for prognosis as well as clinical management of patients. Histopathology is considered gold standard in the diagnosis of benign STT. To study the clinicopathological profile of benign STT in terms of incidence, age, sex, site distribution, gross and histopathological features and their correlation with clinical diagnosis.This descriptive study included 249 patients with benign STT whose excision specimens were analyzed in the Department of Pathology over five years from January 2013 to December 2017.Benign STT constituted 14.7% of all types of neoplasms in the present study. Among STT, benign tumors formed the majority (92.2%). Adipocytic tumors formed the most common histologic group. Benign STT showed a slight male preponderance with peak incidence in the fourth decade. The most common site of occurrence was the trunk followed by head and neck.With this study, we were able to reassess the clinicopathological profile of benign soft tissue STT and their different types with respect to age, sex, and site distribution.

show abstract

Study of soft tissue sarcomas over a period of 3 years

Cited by 3 publications

References 8 publications

Design of Site‐Specific Microwave Phased Array Hyperthermia Applicators Using 434 MHz Reduced Cavity‐Backed Patch Antenna

Design of Site‐Specific Microwave Phased Array Hyperthermia Applicators Using 434 MHz Reduced Cavity‐Backed Patch Antenna

Middle East observational study in metastatic soft tissue sarcoma: an epidemiological study on the treatment patterns (MOON)

Clinico-pathological study of soft tissue tumors

Contact Info

Product

Resources

About