Study of solute retention in reversed-phase high-performance liquid chromatography on hydrocarbonaceous and three fluorinated bonded phases

Synthesis, characterisation and chromatographic evaluation of pentafluorophenyl and phenyl bonded silica phases prepared using supercritical carbon dioxide as a reaction solvent

“…The electron-withdrawing power of fluorine decreases retention of fluorophenyl phases through dispersion forces. Sadek and Carr reported similar observation in comparing the selectivity of fluoro-phases to alkyl phases, partly due to the low polarisation of fluorinated ligands [73].…”

Preparation of branched-polyfluoroalkylsilane-coated silica gel columns and their HPLC separation characteristics

“…The silica gel was treated with the fluorinated silylation agents according to published procedures with some modifications [37]. The silica gel was dried at 220 ~ for 2 h in vacuo.…”

The requisite level of theory for the computational design of molecularly imprinted silica xerogels

“…At the first impression, the high rank of C 6 F 5 TMOS seems surprising since the other hydrophobic functional monomers, C 8 TMOS and PhTMOS exhibited the lowest affinities for the template. However, it is well known that pentafluorophenyl-functionalized silica presents good chromatographic retention properties for Lewis bases possessing, among others, the ketonic group (Sadek and Carr, 1984). The elucidation of the retention mechanism remains largely unexplained.…”