Study of Solvation Behavior of Some Biologically Active Compounds in Aqueous Barium Chloride Solution

Abstract

The density (ρ), viscosity (η), refractive index (n D), and speed of sound (u) of glycine, l-alanine, and l-valine have been determined in different mass fractions (w 1 = 0.01, 0.03, 0.05) aqueous barium chloride solutions at 298.15 K. The limiting apparent molar volumes (ϕ V 0), experimental slopes (S V *) have been found out from the Masson equation. A and B coefficients have been obtained from the Jones–Dole equation. The Lorentz–Lorenz equation has been employed to measure molar refractions (R). Limiting apparent molar adiabatic compressibilities (ϕK 0) of the studied amino acids at infinite dilution have also been measured. These derived parameters have been used to explore solute–solute and solute–solvent interactions in the solutions.

Densities and Speeds of Sound of Solutions of Glycine, l-Alanine, and l-Valine in Aqueous Ammonium Dihydrogen Phosphate at Different Temperatures

“…Ample research − has been carried out on thermodynamic properties of amino acids in aqueous electrolyte solutions, carbohydrates, surfactants, etc. but the phosphates salts are still found in limited study. − The phosphates are biologically and industrially important salts which are employed in food, cosmetics, and pharmaceutical industries and also in numerous biochemical studies. − The present work is just a continuation of our earlier laboratory work on the volumetric and ultrasonic properties of amino acids and peptides with phosphate salts of biological importance. − To explore more on phosphate salts, we hereby delineate the densities and speeds of sound of glycine, l -alanine and l -valine in aqueous ammonium dihydrogen phosphate (ADP) solutions at different temperatures (288.15, 298.15, 308.15, and 318.15) K and atmospheric pressure.…”

Effect of potassium phosphate buffer on volumetric behavior of glycine in aqueous solutions at different temperatures

“…The phosphate buffer system, important in intracellular fluid, consists of conjugate acid-base pair H 2 PO 4 − , as proton donor, and HPO 4 2− , as proton acceptor tends to resist change in pH in the range of (6.1 to 7.7) and would therefore be effective in providing buffering power in intracellular fluid whose pH is in the range of (6.9 to 7.4). Extensive work has been done on thermodynamic properties of amino acids and peptides in aqueous and mixed aqueous solutions of various additives which provide information about solute-solvent and solute-solute interactions operating in these systems [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]. However, these studies were not focused on physiological conditions or biological environment, i.e.…”