Study of solvation behaviour and interactions of drug betaine hydrochloride in aqueous-D-xylose/L-arabinose solutions at different temperatures by using volumetric, acoustic and viscometric methods

Volumetric, Viscometric, and Refractive Index Studies of Drug Nicotinic Acid in Aqueous d-Xylose/l-Arabinose Solutions from 293.15 to 313.15 K: Insights into Solute–Solute and Solute–Solvent Interactions

“…When the hydroxyl groups of the two carbohydrates interact with the hydrophilic sites of nicotinic acid molecules, the hydrogen bond interactions in aqueous l -arabinose solution are stronger than those in aqueous d -xylose solution because of steric hindrance. , On the other hand, the enhancement of solute–solvent interactions due to the position of the hydroxyl group weakens the hydrophilic–hydrophilic interaction between the two nicotinic acid molecules, which results in the decrease in the S v values for aqueous l -arabinose solution . Similar trends for V ϕ 0 and Δ trs V ϕ 0 values were also observed by Nain et al for isoniazid, l -proline, betaine hydrochloride, and sodium salicylate in aqueous d -xylose / l -arabinose solutions.…”

“…Among the numerous carbohydrates, d -xylose is a naturally occurring five-carbon carbohydrate found in a variety of mature fruits. Importantly, it not only can improve the body’s immune capacity by proliferating bifidobacteria in the human gut but also can be used as a calorie-free sweetener for obese and diabetic patients . In addition to its applications in the field of medicine, d -xylose is also widely used in the food industry and has great social and economic value.…”

Volumetric Study of Saccharide Interactions (D-Arabinose, D-Xylose, and D-Galactose) in Sodium Saccharin at 298.15 K

“…The thermodynamic research on saccharides in aqueous solutions have enormous implications in a variety of fields, including science, medicine, and catalysis. The interactions between metal ions and blended electrolyte saccharides have been extensively studied both experimentally and theoretically [6][7][8][9][10][11][12][13][14][15][16]. For solutesolvent and solute-solute interactions, the research of metal ions in aqueous medium containing saccharides is important.…”